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  • Observation of edge solitons and transitions between them in a trimer circuit lattice

    Observation of edge solitons and transitions between them in a trimer circuit lattice

    Implementation of a nonlinear trimer EC lattice and the realization of quench dynamics

    Although the Su-Schrieffer-Heeger lattice is the prototypical model of a topological lattice, we here investigate a one-dimensional trimer lattice with onsite…

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  • Development and validation of questionnaire-based machine-learning models to predict early natural menopause: a national cross-sectional study

    Development and validation of questionnaire-based machine-learning models to predict early natural menopause: a national cross-sectional study

    Study population

    The Epidemiological Health Survey on Early Menopause in Chinese Women is a nationwide multi-center study. From September 1, 2023, to February 5, 2024, researchers conducted an epidemiological survey on the menopausal status of…

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  • Substrate-aware computational design of two-dimensional materials

    Substrate-aware computational design of two-dimensional materials

    Automatic self-consistent training of MLIPs

    In order to train the interatomic potential used in our work, we developed the automatic self-consistent training (ASCT) algorithm based on iterative sampling of the new structures from the molecular…

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  • Human brain organoids reveal new path for Alzheimer’s drugs

    Human brain organoids reveal new path for Alzheimer’s drugs

    Nature, Published online: 21 August 2025; doi:10.1038/d41586-025-02628-1

    Organ models with hallmarks of the disease show marked improvement when a protein’s levels are restored.

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  • Integrative Mendelian randomization and multi-omics analysis identifies anti-allergic drug targets associated with cardiovascular disease risk

    Integrative Mendelian randomization and multi-omics analysis identifies anti-allergic drug targets associated with cardiovascular disease risk

    A comprehensive MR analysis was performed on 139 eQTLs linked to anti-allergic drugs within discovery cohorts of 122,733 CAD patients, 68,157 HF patients, 395,795 MI patients, and 60,620 AF patients. Subsequently, these eQTLs were validated in…

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  • Synthesis of an efficient MOF heterogeneous catalyst (UiO-66-NH2–Pd) for C–O cross-coupling reactions

    Synthesis of an efficient MOF heterogeneous catalyst (UiO-66-NH2–Pd) for C–O cross-coupling reactions

    The XRD patterns of UiO-66-NH2 and UiO-66-NH2–Pd are illustrated in Fig. 3. The UiO-66-NH2 samples exhibit distinct sharp peaks, consistent with previously reported patterns, indicating their excellent crystallinity. As shown in Fig. 3, the…

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  • Future Atlantification of the European Arctic limited under sustained global warming

    Future Atlantification of the European Arctic limited under sustained global warming

    Modern Atlantification

    The clustering algorithm applied to ORAS5 yields the current Atlantic domain to mainly encompass the southern side of the European Arctic, the West Spitsbergen area, the area close to the Barents Sea Opening and the southern…

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