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  • Utility of 3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde in the synthesis of novel 1,3,4-thiadiazoles or 1,3-thiazoles and study their cytotoxic activity

    Utility of 3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde in the synthesis of novel 1,3,4-thiadiazoles or 1,3-thiazoles and study their cytotoxic activity

    Chemistry

    In our research program we utilized 3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde (1)49 as a precursor for synthesis of new heterocycles. Thus, condensation of compound 1 with benzyl or methyl hydrazinecarbodithioates 2a,

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  • Discrete event simulation and agent-based modelling of distributed situation awareness in patient flow management

    Discrete event simulation and agent-based modelling of distributed situation awareness in patient flow management

    This study employed DES and ABM to simulate the current and hypothetical operations of interhospital transportation at a level 1 trauma center for studying and assessing SA distribution and transactions quantitatively. In this study, the DES…

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  • Increasing temperatures counteract the evolutionary consequences of fishing in model of Northeast Arctic Cod (Gadus morhua)

    Increasing temperatures counteract the evolutionary consequences of fishing in model of Northeast Arctic Cod (Gadus morhua)

    Overview

    We utilise an individual-based, mechanistic model containing heritable traits and emergent evolution with explicit energy and oxygen budgets which impact growth, survival, and reproduction of the fish. The model has been parameterized for…

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