Animals and drugs
Male C57BL/6 J mice (8 weeks old; 22–25 g) were used for experiments. The animals were housed in the Laboratory Animal Center of Chongqing Medical University, with 12-h light and dark cycles and the same sleeping conditions….
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Property-driven localization and characterization in deep molecular representations
Radford, A. et al. Improving Language Understanding by Generative Pre-training (2018).
Ke, Z. et al. Continual learning of language models. Preprint at http://arxiv.org/abs/2302.03241 (2023).
Whitney, W. F., Song, M. J., Brandfonbrener, D.,…
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Selective deletion or preservation of tissue components via enzymatic digestion monitored by scanning acoustic microscopy
Human and mouse specimen Preparation
Tissue samples were fixed in a 10% buffered formalin solution, embedded in paraffin and sliced into flat Sect. (10-µm-thick sections were prepared for SAM, whereas 4-µm-thick sections were prepared for LM)….
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Risk factors for hospital-acquired pressure injury in neurosurgery inpatients: a real-world prospective cohort study
Research design and object
This study is a prospective cohort study adhering to the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. It was registered with the Chinese Clinical Trial Registry (
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Design of a novel and robust 2-DOF PIDA controller based on enzyme action optimizer for ball position regulation in magnetic levitation systems
Magnetic levitation systems are characterized by their inherent instability and nonlinear dynamics, presenting significant challenges in achieving precise and robust control of ball position1,2. Parameter uncertainties due to environmental…
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Soft actor-critic algorithm and improved GNN model in secure access control of disaggregated optical networks
Multi-dimensional attack detection performance analysis
To evaluate GESAC’s improvements in threat detection, the study extracted various attack samples from integrated datasets, including: (1) Emerging threats, such as wavelength eavesdropping…
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Nanoantennas and metasurfaces tailored by electron beam lithography and substrate conductivity
Exposure analysis
In our analysis, the exposure dose k is a dominant factor that influences the size of the nanoantenna. To approximate the measurement results and analyze the nanoantenna dimensions, we use the relation \(r = -a \cdot \text…
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Understanding patient needs and preferences for joint protection in hand osteoarthritis through mixed methods patient co-design
Population characteristics
A total of 196 patients (169 women, 22 men) with HOA responded to the survey. The mean age was 66 years old (SD: 8). Thirty-one (16%) of the participants had been experiencing symptoms for more than three months but…
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Introducing a mindfulness-based intervention in school curriculum to 16–24-year-olds. A nationwide cluster-randomized trial
The trial is reported in line with Consolidated Standards of Reporting Trials guidelines for cluster-randomized controlled trials24. The study design and procedures are presented in detail in the published trial protocol25.
Study design and…
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COVID-19 pandemic resulted in more metastatic breast cancer cases at diagnosis
In the current study, we reported and compared breast cancer patients from the pre-pandemic, COVID-19 pandemic, and post-pandemic times, from a tertiary center located in an Eastern-European country. We found that the number of malignant cases…
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