Single-cell data quality control
To ensure data quality across multiple samples, cells with fewer than 500 genes detected were removed according to the filtering formula: (nFeature_RNA > 200 & percent.mt < = median + 3MAD &…
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Inflammation and limited adaptive immunity predict worse outcomes on immunotherapy in head and neck cancer
Chow, L. Q. M. Head and neck cancer. N. Engl. J. Med. 382, 60–72 (2020).
Johnson, D. E. et al. Head and neck squamous cell carcinoma. Nat. Rev. Dis. Primers 6, 92 (2020).
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The impact of the war in Ukraine on the well-being of German medical students: a mixed-methods study
Lievens, F., Ones, D. S. & Dilchert, S. Personality scale validities increase throughout medical school. J. Appl. Psychol. 94, 1514–1535 (2009).
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Panchu, P., Ali, S. L. & Thomas,…
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Observation of a bilayer superfluid with interlayer coherence
Monte Carlo simulation
We use classical Monte Carlo simulations to obtain the many-body thermal state of our interacting system at nonzero temperature. To perform these simulations, we discretize real space on a 2D square lattice and represent the…
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World model-based end-to-end scene generation for accident anticipation in autonomous driving
The primary objective of this study is to predict the likelihood of an accident occurring based on dashcam video footage and to issue an early warning. Formally, let X = {x0, x1, …, xT} represents a sequence of observed video frames,…
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Multicentre retrospective observational study for development and validation of MAC prognostic score model
Patients characteristics
During the study period, 1,317 patients were newly diagnosed with NTM-PD. The final analysis included 1,165 cases, with 139 cases excluded because of non-MAC-PD (Fig. 1). The mean age was 70.7 years, and 371 (31.8%) were…
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Refining renal response assessment in monoclonal immunoglobulin deposition disease: Challenges, limitations and need for consensus
Cohen C, Joly F, Sibille A, Javaugue V, Desport E, Goujon JM, et al. Randall-type monoclonal immunoglobulin deposition disease: new insights into the pathogenesis, diagnosis and management. Diagnostics. 2021;11:420.
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Standard and non-standard framing effects: a unified rational interpretation based on the new definition of frame
In a risky decision experiment concerning the “Asian disease problem” (referred to as the Asian disease experiment), Tversky and Kahneman (1981) observed that when the scenario was described as “lives saved,” the majority of individuals…
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Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP
Bioinformatic analysis of TcPOP and TcPOP homologues
Protein sequences were extracted from the Uniprot database36 for TcPOP (Q71MD6), TbPOP (Q38AG2), LiPOP (A4ICB5), and HuPOP (P48147) and aligned in BLASTP37 to retrieve the top 100 homologues of…
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