Brenda Namumba, shown receiving her PhD, would not have switched from teaching in a secondary school to become an astronomer without the scholarships and encouragement she received. Credit: Brenda Namumba
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Digital twins and Big AI: the future of truly individualised healthcare
Foundational Research Gaps and Future Directions for Digital Twins | National Academies. https://www.nationalacademies.org/our-work/foundational-research-gaps-and-future-directions-for-digital-twins.
Coveney, P. V. & Highfield R. Virtual You: How…
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Observer based resilient security control for networked nondeterministic Markovian jump systems with cyber attacks and its applications
In this section, new stability conditions for the system (8) will be derived based on the Lyapunov stability theory and linear matrix inequality approach, where observer-based resilient event-triggered controllers gain matrices can be obtained….
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Canonical Wnt signaling regulates Mbd3 protein stability during neurogenesis
Canonical Wnt signaling promotes Mbd3 protein stability
Our previous study explored the close association between Mbd3 and the neurogenesis potential of NPCs30. In addition, emerging evidence has identified the Wnt signaling pathway as a factor…
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G-quadruplexes define promoter identity in mammals
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This is a summary of: Esnault, C. et al. G-quadruplexes are promoter elements controlling nucleosome…
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Synthesis and evaluation of novel thiohydantoin derivatives for antidiabetic activity using in silico in vitro and in vivo methods
Chemicals and equipment
Daejung (South Korea) and Alfa-Aesar (Germany) provided all of the raw ingredients. Digital Sanyo-Gallenkamp equipment was used to record the final goods’ uncorrected melting points. The Bruker AM-300 was used to record…
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Silver coated porous silicon microarray SERS platform for detecting aflatoxin B1 fumonisin B1 and ochratoxin A
Materials
Boron-doped Si wafers, <100> face orientation with 0.8–1.0 mΩ cm resistivity, were purchased from Siltronix (France). Methanol (MeOH), hydrofluoric acid (48%), absolute ethanol, AgNO3 (≥99%), DTNB ( ≥ 98%), hydrogen peroxide…
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US senators tell scientists they want to protect NIH budget
Attendees at a meeting of a US Senate appropriations committee on 31 July: from left, Patty Murray, a Democrat from Washington state; Susan Collins, a Republican from Maine; and Mitch McConnell, a Republican from Kentucky.Credit: Tom…
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IC2Bert: masked gene expression pretraining and supervised fine tuning for robust immune checkpoint blockade (ICB) response prediction
Datasets
We employed 13 immune checkpoint blockade (ICB) response cohorts derived from 11 published studies, encompassing a total of 1,214 patients (31.8% responders). Metastatic melanoma was the most frequently studied cancer type, while other…
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Electrochemical investigation of oxytrol in fizzy drinks and juices via graphene and polymer printed PVC by ANOVA and design expert
Electrochemical behavior of sensors
Calibration was done by submerging the electrode in oxytrol solutions with a double junction Ag/AgCl reference electrode across a concentration range of 1.0 × 10–9–1.0 × 10–2 mol L−1 to…
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