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  • Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics

    Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics

    IL-1 pulse duration produces a monotonic correlation between same-cell IKK and NF-κB responses

    We previously developed a CRISPR-modified U2OS cell line that co-express FP fusions of NEMO (EGFP-NEMO) and RelA (mCh-RelA) from their endogenous loci….

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  • Why crop yields fail to increase in southern Africa

    Why crop yields fail to increase in southern Africa

  • Evans, L. T. & Fisher, R. A. Crop Sci. 39, 1544–1551 (1999).

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  • Funk, C. et al. Q. J. R. Meteorol. Soc. 144, 360–383 (2018).

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  • Audiovisual virtual reality for emotion induction: a dataset of physiological responses

    Audiovisual virtual reality for emotion induction: a dataset of physiological responses

    All participants provided informed consent according to the World Association Declaration of Helsinki before the experiment, following ethical guidelines approved by the Ethical Committee of Tecnologico de Monterrey, number:…

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  • Author Correction: Multiscale dynamic immunomodulation by a nanoemulsified Trojan-TLR7/8 adjuvant for robust protection against heterologous pandemic and endemic viruses

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  • Optimizing electric vehicle energy consumption prediction through machine learning and ensemble approaches

    Optimizing electric vehicle energy consumption prediction through machine learning and ensemble approaches

    Data collection and description

    The statistics about EV charging stations in Colorado come from automated systems that track different aspects of charging sessions. These systems are located at city-owned charging stations and record key details…

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  • Accelerated wound healing through tannin-rich Jaft extract, concentration-dependent efficacy and mechanistic insights from Quercus brantii ointment formulations

    Accelerated wound healing through tannin-rich Jaft extract, concentration-dependent efficacy and mechanistic insights from Quercus brantii ointment formulations

    Reactive oxygen species (ROS) play a dual role in wound healing, where both excessive production and inadequate detoxification can lead to oxidative stress, exacerbating inflammation and delaying tissue repair12. This underscores the importance…

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  • Autumn leaf color brightness of Japanese alpine vegetation is projected to decrease under future climate change

    Autumn leaf color brightness of Japanese alpine vegetation is projected to decrease under future climate change

  • Fox, N. et al. A novel data source for cultural ecosystem service studies. Ecosyst. Serv. 50, 101331. https://doi.org/10.1016/j.ecoser.2021.101331 (2021).

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  • Hernandez-Morcillo, M.,…

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  • Sustainable packaging using Aloe vera infused mango starch–wool keratin biocomposite films to extend the shelf life of mango

    Sustainable packaging using Aloe vera infused mango starch–wool keratin biocomposite films to extend the shelf life of mango

    13C NMR spectroscopy

    The 13C solid-state nuclear magnetic resonance spectrum of mango seed kernel starch (Fig. 1) showed well-defined chemical shifts consistent with typical polysaccharide structures. The observed…

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  • Suicide gene therapy targeting ewing sarcoma via an ewing-specific GGAA promoter

    Suicide gene therapy targeting ewing sarcoma via an ewing-specific GGAA promoter

    Cell lines

    The Ewing sarcoma cell line A673 (CRL-1598), the fibrosarcoma cell line HT1080 (CCL-121) and the osteosarcoma cell lines U2-OS (HTB-96) and Saos-2 (HTB-85) were purchased from the American Type Culture Collection (Manassas, VA, USA)….

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