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  • Optical control of gene expression using a DNA G-quadruplex targeting reversible photoswitch

    Optical control of gene expression using a DNA G-quadruplex targeting reversible photoswitch

    Chemical synthesis and characterizations

    Full synthesis and characterization of molecules, photoisomerization details, UV–visible spectroscopy, cell viability assays, western blotting and general information are described in Supplementary…

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  • Evaluation of ecological consequences on the global distribution of Staphylococcus aureus Rosenbach 1884 due to climate change, using Maxent modeling

    Evaluation of ecological consequences on the global distribution of Staphylococcus aureus Rosenbach 1884 due to climate change, using Maxent modeling

    Model assessment and contribution of environmental variables

    The MaxEnt model employed to forecast the appropriateness of habitats for Staphylococcus aureus exhibited exceptional performance, as seen by the elevated Area Under the Curve (AUC)…

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  • Correction: Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area

    The article “Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area”, written by Yue-ying L., Ke W., Yu-ting D., Ru. J, Xing-han C., An-yu G., Jun-li…

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  • Unequal signalling and biosynthesis in daughter cells

    Unequal signalling and biosynthesis in daughter cells

    The stem cells in the root apical meristem divide to give rise to transit-amplifying cells, which eventually exit from the cell cycle for elongation and differentiation. Low levels of brassinosteroids are required for cell cycle progression in…

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  • Correction: NF-κB-mediated EAAT3 upregulation in antioxidant defense and ferroptosis sensitivity in lung cancer

    Correction: NF-κB-mediated EAAT3 upregulation in antioxidant defense and ferroptosis sensitivity in lung cancer

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  • Comprehensive germline and somatic profiling of high-risk Thai breast cancer via next-generation sequencing

    Comprehensive germline and somatic profiling of high-risk Thai breast cancer via next-generation sequencing

    Spectrum of germline mutations in Thai patients with breast cancer and cross-ethnic comparisons

    Blood samples from 1370 patients were subjected to germline mutation sequencing using a custom 36-core cancer panel (Supplementary Table 1). We found…

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  • Molecular characterization of newly diagnosed acute myeloid leukemia patients aged 60 years or older: a report from the Beat AML clinical trial

    Molecular characterization of newly diagnosed acute myeloid leukemia patients aged 60 years or older: a report from the Beat AML clinical trial

    Competing interests

    WGB has served on advisory boards of AbbVie and Syndax and has research funding from ImmuneOnc, Meryx, and Nkarta. ET has participated in advisory boards and/or consulting for…

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  • Improving diagnostic accuracy in atypical melanocytic tumors using p16 immunohistochemistry and 9p21 fluorescence in situ hybridization: analysis of 206 second opinion cases

    Improving diagnostic accuracy in atypical melanocytic tumors using p16 immunohistochemistry and 9p21 fluorescence in situ hybridization: analysis of 206 second opinion cases

    According to the selection criteria, we identified and studied 206 atypical melanocytic tumors that had been evaluated with 9p21 FISH and p16 IHC (summarized in Supplementary Table 1; see supplemental digital content containing 2 tables).

    Clinical…

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  • Increased risk of cardiomyopathy in individuals with methamphetamine related disorders in Taiwan

    Increased risk of cardiomyopathy in individuals with methamphetamine related disorders in Taiwan

    Data source

    Since 1995, Taiwan’s Ministry of Health and Welfare has maintained the National Health Insurance Research Database (NHIRD), This study utilized data from the Longitudinal Health Insurance Database (LHID), a subset of the NHIRD which…

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