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  • Spectral shaping technology reduces the radiation dose of CT-guided lung tumor microwave ablation

    Spectral shaping technology reduces the radiation dose of CT-guided lung tumor microwave ablation

    Study design and subjects

    This prospective, randomized, double-blind, non-inferiority trial was approved by the local institutional ethics committee, and informed consent was obtained from all eligible patients. We assessed 131 patients indicated…

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  • Lipid nanoparticles with PDL1-encoding mRNA spread tolerance

    Tolerogenic antigen-presenting cells (APCs) downregulate the responses of effector T cells or promote the differentiation of regulatory T (Treg) cells, and APC-based immunotherapies have been explored to target autoimmune diseases. Some…

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  • A significant correlation exists between CREBBP and CEBPA gene expression in de Novo adult acute myeloid leukemia

    A significant correlation exists between CREBBP and CEBPA gene expression in de Novo adult acute myeloid leukemia

    The present study assessed CREBBP, CEBPA, and DNMT3A expression in 53 adult AML patients from Egypt. Inconsistent with the literature, the present study detected the expression of CEBPA and DNMT3A in almost all samples, with frequencies of 88.7%…

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  • Diffuse pulmonary ossification and its association with cicatricial organising pneumonia in idiopathic and secondary forms

    Diffuse pulmonary ossification and its association with cicatricial organising pneumonia in idiopathic and secondary forms

    Selection of patients with DiPO

    The data from 39 patients were initially available for analysis with the assistance of the collaborators. One patient with pulmonary osteochondroma and 13 patients with unavailable histopathological specimens or…

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  • A multi-institutional cohort study on risk of sleep disorders in dry eyes patients using TriNetX

    A multi-institutional cohort study on risk of sleep disorders in dry eyes patients using TriNetX

    The relationship between sleep disorders and DED is increasingly acknowledged, highlighting the complex interactions between physiological and psychosocial factors. To the best of our knowledge, this is currently the only large-scale, multicenter…

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  • Emotional distress during the first year of the COVID-19 pandemic-large sample serbian study

  • Jovic, J. et al. Internet use during coronavirus disease of 2019 pandemic: Psychiatric history and sociodemographics as predictors. Indian J. Psychiatry 62, S383–S390 (2020).

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    PubMed Central 

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  • Per and polyfluoroalkyl substances affect thyroid hormones for people with a history of exposure from drinking water

    Per and polyfluoroalkyl substances affect thyroid hormones for people with a history of exposure from drinking water

    Study design and population

    From December 2020 to August 2021, we recruited 1,054 individuals into the first phase of the longitudinal Michigan PFAS Exposure and Health Study (MiPEHS), based in Michigan, USA. To be eligible for MiPEHS,…

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  • Pre-symptomatic Parkinson’s disease blood test quantifying repetitive sequence motifs in transfer RNA fragments

    Pre-symptomatic Parkinson’s disease blood test quantifying repetitive sequence motifs in transfer RNA fragments

    Ethics statement

    Ethics approval for this study was confirmed by the Hebrew University’s committee for research involving human-derived materials. Blood samples of the JLM cohort were collected at the Shaare Zedek Medical Center in Jerusalem…

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  • A lightweight large receptive field network LrfSR for image super-resolution

    A lightweight large receptive field network LrfSR for image super-resolution

    The LrfSR network model proposed in this paper is illustrated in Figure 2, and its image processing pipeline consists of three stages: shallow feature extraction, deep feature extraction, and image reconstruction (corresponding to the content of…

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