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  • The impact of psychological capital on job performance among government employees in China

    The impact of psychological capital on job performance among government employees in China

    Basic questionnaire information

    This survey involved a total of 2,357 government employees, with males accounting for 44.1% and females accounting for 55.9%, indicating a slightly higher participation rate among females, as shown in Table 1. In…

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  • A nutrient wide association study of cardiovascular disease prevalence in older adults from NHANES 2007 to 2018

    A nutrient wide association study of cardiovascular disease prevalence in older adults from NHANES 2007 to 2018

    Study population characteristics

    The study included 7,341 participants, of whom 2,033 (27.7%) had CVD (Table 1). Participants with CVD were older (mean age 74.58 vs. 72.94 years, P < 0.001) and had a lower poverty-to-income ratio (PIR) compared…

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  • Oncolytic peptide LTX-315 plus an anti-CTLA-4 antibody induces a synergistic anti-cancer immune response in residual tumors after radiofrequency ablation of hepatocellular carcinoma

    Oncolytic peptide LTX-315 plus an anti-CTLA-4 antibody induces a synergistic anti-cancer immune response in residual tumors after radiofrequency ablation of hepatocellular carcinoma

    Study design

    This study consisted of two phases: (1) in vitro exploration of the enhancing effect of LTX-315 plus an anti-CTLA-4 antibody on the cytotoxicity of CD8+T cells for HCC cells after iRFA of HCC and the underlying mechanisms, and (2) in…

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  • Gene expression profile of anoikis reveals new subtypes of liver cancer and discovery of therapeutic targets and biomarkers

    Gene expression profile of anoikis reveals new subtypes of liver cancer and discovery of therapeutic targets and biomarkers

    The development of liver cancer is closely related to Anoikis

    We obtained the RNA-seq data of patients with liver cancer and normal controls in TCGA database, and analyzed the mutation load and difference of anoikis-related genes. We found that…

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  • Prioritizing mental health support for physician-scientist trainees

    The highly structured nature of MD/DO-PhD programs in the U.S. presents unique opportunities for targeted mental health interventions that could be adapted globally. While these programs offer substantial but highly competitive funding…

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