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  • Long-term GABA supplementation mitigates anxiety by modulating complement and neuroinflammatory pathways

    Long-term GABA supplementation mitigates anxiety by modulating complement and neuroinflammatory pathways

    In this study, we evaluated the anxiolytic effects of oral GABA supplementation and its impact on complement activation and inflammation in mice with CRS. 1) Following 14 days after oral GABA administration (20 mg/kg), we demonstrated that GABA…

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  • Rational design of synthetic antimicrobial peptides based on the Escherichia coli ShoB toxin

    Rational design of synthetic antimicrobial peptides based on the Escherichia coli ShoB toxin

    Type-I TA systems are abundant in bacterial genomes, and their toxin counterparts have been shown to exert potent killing effects when overexpressed23. The toxins therefore constitute interesting starting points for development of unique…

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  • A novel strategy for Escherichia coli detection in raw beef in combination with click chemistry

    A novel strategy for Escherichia coli detection in raw beef in combination with click chemistry

    Materials

    Tetrachloroauric(III) acid (HAuCl4·3H2O), 11-azido-3,6,9- trioxaundecan-1-amine, N-ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC),11-mercaptoundecanoic acid, Hydroxy-2,5-dioxopyrrolidine-3-sulfonicacid sodium salt…

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  • Quantifying the trade-offs between renewable energy visibility and system costs

    Quantifying the trade-offs between renewable energy visibility and system costs

  • Intergovernmental Panel on Climate Change (IPCC). Mitigation Pathways Compatible with 1. 5°C in the Context of Sustainable Development (Cambridge Univ. Press, 2022).

  • Wiser, R. et al. Expert elicitation survey on future wind energy costs. Nat….

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  • Flood fatalities and displacement influence human migration in floodplains of developing countries

    Flood fatalities and displacement influence human migration in floodplains of developing countries

    Characteristics of human migration and potential drivers in floodplain areas

    We use the slope of human-flood distance (HFD in meters) to represent human migration (HFDS, km per year) within floodplain areas from 2000 to 2018. Figure 1a…

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  • A new method to improve the power quality of photovoltaic power generation based on 24 solar terms

    A new method to improve the power quality of photovoltaic power generation based on 24 solar terms

    Current research indicates that voltage instability is one of the primary challenges in power systems with intermittent PV power generation25,26,27. The peak and valley values of PV power generation have a significant impact on the stability of…

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  • Differential unfolded protein response regulation in KRAS silencing sensitive and innately resistant colorectal cancer cells

    Differential unfolded protein response regulation in KRAS silencing sensitive and innately resistant colorectal cancer cells

    Cell lines

    CRC cell lines HCT116 (RRID: CVCL_0291) and SW480 (RRID: CVCL_0546) were purchased from the American Type Culture Collection (ATCC). LS174T cells were kindly provided by Dr. Ragnhild A. Lothe (Oslo University Hospital, Norway). SW837…

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  • Structural and electrochemical properties of ternary solid polymer electrolytes based on PVA:CS:FSG doped with sodium thiocyanate

    Structural and electrochemical properties of ternary solid polymer electrolytes based on PVA:CS:FSG doped with sodium thiocyanate

    X-ray diffraction study

    The XRD technique has been nominated as a powerful tool in the field of material science and engineering. It relies on the capacity of crystals to diffract X-rays in a distinctive way, enabling an accurate examination of…

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  • Author Correction: Quantifying both socioeconomic and climate uncertainty in coupled human–Earth systems analysis

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