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Exploring differences in signaling pathways of the circadian clock and neuromodulators in obstructive sleep apnea
Obstructive sleep apnea (OSA) is a disorder marked by recurrent partial or complete obstructions of the upper airway during sleep, resulting in disrupted sleep architecture and systemic consequences1,2,3,4. The pathogenesis of OSA is…
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Brain circuits that regulate social behavior
Circuit mechanisms underlying general social investigation
Social investigation is characterized by the close examination of social stimuli, a process that relies on the integration of multiple sensory cues to gather sufficient information before…
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Unveiling Berberine analogues as potential inhibitors of Escherichia coli FtsZ through machine learning molecular docking and molecular dynamics approach
Performance of different machine-learning (ML) classifiers and data set training
To develop an optimal ML model for differentiating anti-FtsZ compounds from non-inhibitory compounds, we built classification model using ML techniques. The…
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Accurate quantification of cell-free Ceruloplasmin mRNA as a biomarker for early detection of hepatocellular carcinoma
Study population characteristics
The study included 103 participants divided into three main groups (Table 2): 51 patients with hepatocellular carcinoma (HCC), 21 patients with chronic liver disease (CLD) and 31 healthy donors (HD). The median age…
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RFID-embedded mattress for sleep disorder detection for athletes in sports psychology
Smart RFID-embedded mattress design
A mattress (152 mm × 196 mm) embedded with passive RFID sensors (7 × 49 = 343) was developed to detect and track an athlete’s sleep posture. These sensors were positioned as a matrix to monitor…
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Unravel subseafloor hydrothermal leaching and magmatic degassing during chimney formation at Kolumbo volcano
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Hannington, M., de Ronde, C. E. J. & Petersen, S. Sea-Floor Tectonics and Submarine…
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Global burden of hypertensive heart disease and attributable risk factors, 1990–2021: insights from the global burden of disease study 2021
Global trends
In 2021, the global prevalence of hypertensive heart disease (HHD) was approximated at 12.51 million instances (UI 117.3–132.8), signifying an 18.2% augmentation in contrast to 1990. The age-standardized prevalence rate of HHD…
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Free recall is shaped by inference and scaffolded by event structure
We designed a task that required participants to uncover a hidden rule by making judgments about individual words. The hidden rule underwent unsignaled changes, which required participants to rapidly adapt their model of the ongoing event. For…
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Investigations into cyanobacterial photoacclimation processes address longstanding proposals for improving crop yields
Zhu, X.-G., Long, S. P. & Ort, D. R. Improving photosynthetic efficiency for greater yield. Annu. Rev. Plant Biol. 61, 235–261 (2010).
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Anten, N. P. R….
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