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  • Optimizing MEMS inertial switches for efficient event-based environmental interaction: motivation, approaches, and purposes

    Optimizing MEMS inertial switches for efficient event-based environmental interaction: motivation, approaches, and purposes

  • Sinha, S. State of IoT 2024: Number of connected IoT devices growing 13% to 18.8 billion globally. IOT ANALYTICS. (2024). at https://iot-analytics.com/number-connected-iot-devices/ (Accessed: 6 May 2025).

  • Ren, L., Dong, J. B., Liu, S., Zhang, L. &…

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  • Cathepsin D promotes acute myeloid leukemia progression through stabilization of the anti-apoptotic proteins

    Cathepsin D promotes acute myeloid leukemia progression through stabilization of the anti-apoptotic proteins

    Cell lines

    Human leukemia cell lines HL60, Kasumi, U937, and MV4-11 were purchased from National Collection of Authenticated Cell Cultures (Shanghai, China). Human leukemia KG1 cells was purchased from ATCC (Manassas, Maryland, USA). OCI-AML3 and…

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  • Precise, predictable genome integrations by deep-learning-assisted design of microhomology-based templates

    Precise, predictable genome integrations by deep-learning-assisted design of microhomology-based templates

    Cell culture

    HEK293T (American Type Culture Collection (ATCC), CRL-11268) were cultured as recommended by the ATCC. Cell lines tested negative for Mycoplasma and were authenticated by the suppliers.

    Modeling of gene-editing outcomes

    The inDelphi…

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  • Response to ‘The puzzle of biologics manufacturing platform patents’

    Amgen is the leading manufacturer of both innovative biologics and biosimilar medicines and is uniquely positioned to respond to the “puzzle” of unsupported assertions in the March Patent Feature by Jefferson et al.1. Contrary to their…

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  • DNA polymerase actively and sequentially displaces single-stranded DNA-binding proteins

    DNA polymerase actively and sequentially displaces single-stranded DNA-binding proteins

    Force-dependent regulation of DNA replication by SSB proteins

    The binding of T7 SSB to ssDNA reportedly depends on force-induced ssDNA conformations13, suggesting this interaction may modulate DNA replication in a force-dependent manner. We…

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  • Research status of roof water and sand bursting disaster in thick bedrock stope of coal seam

    Research status of roof water and sand bursting disaster in thick bedrock stope of coal seam

    Geological conditions and occurrence of the accident

    Zhaojin Coal Mine is located in the Xunyao Mining Area, Huanglong Coalfield, Shaanxi Province, China, and mainly mines No.4− 2 coal seams of the Jurassic System. The geological structure of…

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  • Hybrid Kerr-electro-optic frequency combs on thin-film lithium niobate

    Hybrid Kerr-electro-optic frequency combs on thin-film lithium niobate

    Device fabrication and parameters

    DKS devices are fabricated on a commercial Z-cut thin-film lithium niobate (Z-TFLN) on-insulator wafer (NANOLN). The initial film thickness is 600 nm of Z-TFLN on top of 2 μm thermal oxide and 0.525 mm…

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