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  • Model based planning and layout optimization for multilevel express processing centers through A case study of air express sorting center

    Model based planning and layout optimization for multilevel express processing centers through A case study of air express sorting center

    Driven by economic globalization and the vigorous development of e-commerce, the express logistics industry is experiencing unprecedented growth1. As critical nodes in the express logistics network, multi-level express processing centers play a…

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  • Reanalysis of in vivo drug synergy validation study rules out synergy in most cases

    Reanalysis of in vivo drug synergy validation study rules out synergy in most cases

    Instead of testing each drug alone and in their combinations at multiple dose levels, Narayan et al.1 employed a shortcut by testing the single agents and their combinations at only one dose level, thus ignoring the requirement to generate full…

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  • A comprehensive study of the upcycling of litchi chinensis waste into a sustainable transesterification catalyst

    A comprehensive study of the upcycling of litchi chinensis waste into a sustainable transesterification catalyst

    Characterization of Litchi waste catalyst

    The X-ray diffraction (XRD) pattern of the litchi waste derived catalyst calcinated at variable temperatures (600 °C, 750 °C and 900 °C) is illustrated in Fig. 1. The analysis (Fig. 1(a)) showed…

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  • The correlation between different metabolic scores and the risk of cardiometabolic comorbidities in hypertensive patients

    The correlation between different metabolic scores and the risk of cardiometabolic comorbidities in hypertensive patients

    The findings of this study indicate that in the hypertensive population, higher levels of METS-IR, METS-VF, and CMI are associated with an increased risk of CMM. This relationship is particularly pronounced among male hypertensive patients. Our…

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  • Design and evolution of artificial enzyme with in-situ biosynthesized non-canonical amino acid

    Design and evolution of artificial enzyme with in-situ biosynthesized non-canonical amino acid

  • Chen, K. & Arnold, F. H. Engineering new catalytic activities in enzymes. Nat. Catal. 3, 203–213 (2020).

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  • Lovelock, S. L. et al. The road to fully programmable protein…

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  • Immune system development-related signature predicts prognosis and sorafenib-treatment resistance of hepatocellular carcinoma by intergrating machine learning and single-cell analyses

    Immune system development-related signature predicts prognosis and sorafenib-treatment resistance of hepatocellular carcinoma by intergrating machine learning and single-cell analyses

    The clinical significance and potential mechanism of ISD levels

    Figure 1 showed the workflow chart of the whole study. To systematically evaluate the clinical significance and potential mechanism of ISD levels, we first calculated ISD levels and…

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  • Optimizing retinal images based carotid atherosclerosis prediction with explainable foundation models

    Optimizing retinal images based carotid atherosclerosis prediction with explainable foundation models

    Figure 2 presents the overall schema. The dataset (N = 39,620) was divided into two subsets. The first subset (N = 6597) was used to develop carotid atherosclerosis prediction models. This subset was further split into training,…

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  • Impact of epstein-barr virus reactivation on cytokine levels in pregnant women with malaria in the west region of cameroon

    Impact of epstein-barr virus reactivation on cytokine levels in pregnant women with malaria in the west region of cameroon

    Malaria remains the most deadly parasitic disease in sub-Saharan Africa. In Cameroon, all regions are considered malaria-endemic, allowing the co-circulation with other pathogens, such as Epstein-Barr virus, one of the most common viruses in…

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  • Multilingual social media analysis reveals global patterns and language imbalances in volcanic eruption coverage

    Multilingual social media analysis reveals global patterns and language imbalances in volcanic eruption coverage

    The social media service , formerly and popularly known as Twitter, is a microblogging and social networking service. Users of the service can post, interact with, and re-post messages generally referred to as tweets. The service was first…

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