A comprehensive MR analysis was performed on 139 eQTLs linked to anti-allergic drugs within discovery cohorts of 122,733 CAD patients, 68,157 HF patients, 395,795 MI patients, and 60,620 AF patients. Subsequently, these eQTLs were validated in…
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Author Correction: Macrophages excite muscle spindles with glutamate to bolster locomotion
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
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Risk factors for invasive fungal infections in adult patients with hematological malignancies and/or stem cell transplant: a systematic review and meta-analysis
Selection process and characteristics of included studies
Among 12 624 references identified, we assessed 578 studies on full-text to finally include 69 studies (Fig. 1; Table 1), reporting 2 917 IFI in 35 781 episodes. Reasons for exclusion…
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Assessing the performance of the Iceland screens, treats, or prevents multiple myeloma (iStopMM) model in a multicultural Bronx cohort: implications for monoclonal gammopathy of undetermined significance risk stratification
Since MGUS is a pre-malignant condition with approximately 1% annual risk of evolving into MM, a critical aspect in the care of MGUS patients is risk stratification and monitoring [5, 6]. The IMWG risk stratification system utilizes these three…
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High intensity interval training attenuate insulin resistance in diabetic rats accompanied by improvements in liver metabolism and spexin signaling
Body weight and blood glucose concentrations
The data indicated a significant increase in body weight in both T2D and T2D+HIIT compared to CON and HIIT groups after diabetes induction (month 2) (P < 0.0001). However, month 4 body weight was…
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Targeting the roots of myeloid malignancies with T cell receptors
Arber, D. A. et al. International consensus classification of myeloid neoplasms and acute leukemias: integrating morphologic, clinical, and genomic data. Blood 140, 1200–1228 (2022).
…
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Prediction of ultimate load capacity of demountable shear stud connectors using machine learning techniques
Steel–concrete composite beams are widely used in modern construction due to their exceptional strength, stiffness, and structural efficiency. These systems rely on shear connectors to ensure effective force transfer between the steel and…
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A novel hesitant fuzzy tensor-based group decision-making approach with application to heterogeneous wireless network evaluation
In real-world scenarios, especially under uncertain and conflicting expert opinions, decision-makers often hesitate among several possible membership degrees when evaluating an element. This leads to the development of the hesitant fuzzy set…
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Publisher Correction: Tetraspanin-enriched membrane domains regulate vascular leakage by altering membrane cholesterol accessibility to balance antagonistic GTPases
Publisher Correction: Tetraspanin-enriched membrane domains regulate vascular leakage by altering membrane cholesterol accessibility to balance antagonistic GTPases
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Human brain organoids reveal new path for Alzheimer’s drugs
Nature, Published online: 21 August 2025; doi:10.1038/d41586-025-02628-1
Organ models with hallmarks of the disease show marked improvement when a protein’s levels are restored.
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