Deep in the first moments of the Big Bang, the entire cosmos shook and rumbled. Those quakes still reverberate to the present day. It will take the most sensitive instruments ever imagined to reveal those ripples, but if they are discovered,…
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Latent profile analysis and influencing factors of cognitive flexibility among Chinese high school students
Spiro, R. J., Feltovich, P. J., Jacobson, M. J. & Coulson, R. L. Cognitive flexibility, constructivism, and hypertext: Random access instruction for advanced knowledge acquisition in ill-structured domains. educational technology (1992).
Dajani,…
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Sci-Tech finance, digital economy and high-quality development of regional economy: empirical evidence from 273 cities in China
Sample descriptive statistics
To test for the presence of multicollinearity in the variables, the Variance Inflation Factor (VIF) test is performed; the results are presented in Table 2. The maximum VIF value of each variable is 2.165, the minimum…
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Bauhinia monandra derived mesoporous activated carbon for the efficient adsorptive removal of phenol from wastewater
Saxena, V. Water Quality, Air Pollution, and Climate Change: Investigating the Environmental Impacts of Industrialization and Urbanization. Water, Air, and Soil Pollution Vol. 236 (Springer, 2025).
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Structural basis of Fusobacterium nucleatum adhesin Fap2 interaction with receptors on cancer and immune cells
Source of plasmids and genes for design of expression constructs
The E. coli expression vector pAIDA1 was a gift from Gen Larsson (Addgene plasmid #79180; http://n2t.net/addgene:79180; RRID:Addgene_79180)44. The fap2 gene sequence from Fusobacterium…
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Natural allelic variation in SW14 determines seed weight and quality in soybean
Plant materials and growth conditions
The 320 previously sequenced accessions16 utilized for GWAS, and an F2 population (n = 280) and its progenies utilized for fine mapping, were grown under natural conditions from 2018 to 2021 in Guangzhou…
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Clock genes keep intestinal ILC3s ticking
Innate lymphoid cells (ILCs) have crucial roles in maintaining gut homeostasis and providing protection against intestinal infection. Bhattarai et al. describe a role for the circadian clock proteins REV-ERBα and REV-ERBβ in regulating the…
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The deacetylases HDAC1/HDAC2 control JAK2V617F-STAT signaling through the ubiquitin ligase SIAH2
Cell cultures and growth conditions
HEL cells are JAK2V617F-positive human erythroleukemic cells from the peripheral blood of a 30-year-old male with PV in 1980 (AML M6 erythroleukemia, in relapse after treatment for Hodgkin lymphoma). SET-2 cells…
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Accumulation of pathogenic mitochondrial DNA mutations in the kidney
Pathogenic mutations in mitochondrial DNA (mtDNA) are often heteroplasmic: wild-type and mutant mtDNA can exist within a single cell, and the genetic defect manifests when the proportion of mutant mtDNA exceeds a threshold. A study by Min Jiang…
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Stress-inducible phosphoprotein 1 (STIP1) is a critical stemness regulator in mouse embryonic stem cells and early mammalian development
Stip1 is co-expressed with pluripotency transcription factors in the blastocyst
Our group previously showed that STIP1 KO is lethal in mice, with embryos presenting prominent neural tube degeneration, establishing a…
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