Mice
For LD50 and inhibitor experiments, C57BL/6 female mice from Jackson Laboratories (000664) were used. Young mice were used at 12 weeks of age or roughly 12 weeks of age (12–14 weeks). Aged mice were used at 72–76 weeks of age….
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The ubiquitin ligase KLHL6 drives resistance to CD8+ T cell dysfunction
Mice
Male and female mice were used for the study. CD45.1+ OT-I or P14 TCR-transgenic mice were housed together. CD45.2+ male and female C57BL/6N or C57BL/6JNifdc mice aged 6–8 weeks were purchased from Vital River as recipients. Female NCG…
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A nowhere-to-hide mechanism ensures complete piRNA-directed DNA methylation
Aravin, A. A., Sachidanandam, R., Girard, A., Fejes-Toth, K. & Hannon, G. J. Developmentally regulated piRNA clusters implicate MILI in transposon control. Science 316, 744–747 (2007).
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N1-Methylpseudouridine directly modulates translation dynamics
Saxena, S. et al. The future of mRNA vaccines: potential beyond COVID-19. Cureus 17, e84529 (2025).
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Anderson, B. R. et al. Nucleoside modifications in RNA…
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Global subsidence of river deltas
Selection of global river deltas
We selected 40 deltas globally, prioritizing 35 deltaic systems with the greatest exposed area and population currently below sea level, supplemented by five less-exposed deltas of local and regional significance…
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Beneath acid skies
They called her Gretel when she still remembered their names. Unit 40-GRET, Combat-Service Android, was made to protect humanity and to guard the citadel of New Warsaw during the Last Rain. Back then, the skies wept acid, and the cities crumbled…
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Memories of items and their contexts are encoded by separate groups of human brain cells
- RESEARCH BRIEFINGS
Human memory often needs to link specific items to…
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La NASA transmitirá en directo el regreso y el amerizaje de Crew 11
Read this press release in English here.
La NASA y SpaceX prevén que, si las condiciones meteorológicas lo permiten, el desacoplamiento de la misión SpaceX Crew 11 de la agencia espacial estadounidense de la Estación Espacial Internacional…
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U.S. Space Force switches rockets for upcoming GPS satellite launch – Spaceflight Now
The GPS III Space Vehicle 09, the ninth GPS III spacecraft, is pictured traveling by road from Lockheed Martin facilities in Denver, CO, to Florida’s Space Coast. Image: Lockheed Martin The next Global Positioning System satellite is switching…
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Getting a grip on aging: Study pinpoints brain region tied to frailty
A new study suggests that a little-known region deep in the brain could be crucial for preserving physical strength as we age. The findings could help detect and prevent frailty before it begins.
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