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  • Application of a comprehensive approach to pathogen screening in a stowaway rat on an airplane

    Application of a comprehensive approach to pathogen screening in a stowaway rat on an airplane

    Sample collection, dissection and species identification

    All methods were carried out in accordance with relevant national and international guidelines and regulations. The removal of the stowaway rat from the airplane follows the regulations…

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  • Modulating tumor collagen fiber alignment for enhanced lung cancer immunotherapy via inhaled RNA

    Modulating tumor collagen fiber alignment for enhanced lung cancer immunotherapy via inhaled RNA

    Materials

    1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine (DSPC), 1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (DMG-PEG2000), and cholesterol were purchased from AVT (Shanghai) Pharmaceutical Tech Co., Ltd. siPD-L1 and siNC were…

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  • In-cell proximity target validation methods for heterobifunctional molecules with CRBN- or VHL-binder using AirID

    In-cell proximity target validation methods for heterobifunctional molecules with CRBN- or VHL-binder using AirID

    Comparison of interactomes of BRD binder-dependent PROTACs with different E3 binders

    The bromodomain extra-terminal (BET) family proteins, including BRD4 and BRD3, are promising anticancer drug targets27,28. ARV-825 and MZ1 were developed to…

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  • Uneven participation of independent and contract smallholders in certified palm oil mill markets in Indonesia

    Uneven participation of independent and contract smallholders in certified palm oil mill markets in Indonesia

    Study system

    In Indonesia, smallholders often have no control over their status as “independent” or “contract” farmers. This is because oil palm development has been driven by large-scale plantation companies that have typically been…

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  • Predicting postoperative imbalance in adult spinal deformity staged surgery using predictive thresholds

    Predicting postoperative imbalance in adult spinal deformity staged surgery using predictive thresholds

    Demographics, operative parameters, and etiologies

    138 patients were excluded for the following reasons (Fig. 3.): distal fixation was not achieved using S2AI screws for pelvic stabilization (50 patients), incomplete radiographic data (43…

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  • Crude protoscolex antigens of echinococcus granulosus as serological markers for human hydatidosis detection

    Crude protoscolex antigens of echinococcus granulosus as serological markers for human hydatidosis detection

    Human CE is one of the endemic neglected diseases in our region which spreads in rural areas where individuals are in direct contact with dogs and livestock12,13. Imaging techniques are the most reliable method for diagnosis of CE. Serological…

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  • Comparing thermographic heat signatures with joint inflammation detected by ultrasound at the knees in patients with rheumatoid arthritis

    Comparing thermographic heat signatures with joint inflammation detected by ultrasound at the knees in patients with rheumatoid arthritis

    A total of 570 knee (3 aspects per knee) thermograms were obtained while 190 knees (bilaterally) were scanned by ultrasound among 95 RA patients. The patient baseline characteristics and demographic data were as follows: mean (SD) age was 56.7…

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  • Dual-function FeCo bimetallic nanoclusters for ammonia electrosynthesis from nitrate/nitrite reduction

    Dual-function FeCo bimetallic nanoclusters for ammonia electrosynthesis from nitrate/nitrite reduction

    Synthesis and characterization of Fe2Co1/NC

    Figure 1a illustrates the process flow for the preparation of Fe2Co1/NC catalyst loaded on NC using SiO2 as a hard template, with the core steps including precursor impregnation, high-temperature…

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