Sample collection
Human developmental stages E45–E72 were obtained from first-trimester termination procedures conducted at the Birth Defects Research Laboratory (BDRL; supported by National Institutes of Health (NIH) award number 5R24HD000836)…
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Mechanical confinement governs phenotypic plasticity in melanoma
Zebrafish husbandry
Stable transgenic zebrafish lines were kept at 28.5 °C in a dedicated aquatics facility with a 14 h on/10 h off light cycle. Casper fish with the following genotype were used for all experiments:…
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Scientists engineer enzymes to turn crops into recyclable bioplastics
Plastic products frequently pile up in landfills or spill into natural habitats where they occupy space and endanger wildlife.
To combat this problem, a team of university and industry researchers have been awarded funding from the U.S….
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US to boost nuclear fuel, reactor development with uranium allocation
The Department of Energy (DOE) in the United States has taken a significant step to strengthen the efforts for advanced nuclear reactor development. The DOE has made conditional commitments to provide high-assay low-enriched uranium (HALEU) to…
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Adjuvant icotinib for resected EGFR-mutated stage II–IIIA non-small-cell lung cancer (ICTAN, GASTO1002): a randomized comparison study
Patient characteristics
From July 2014 through December 2021, 386 patients were screened for enrollment, and a total of 251 patients were randomly assigned, with 84 patients in the 12-month icotinib group, 84 patients in the 6-month icotinib…
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Frequency-specific neural abnormalities in congenital prosopagnosia revealed by magnetoencephalography during face perception
Subjects
Seventeen healthy controls (HCs) (eleven women; mean age: 28.95 years; range: 19–48 years) and three individuals with congenital prosopagnosia (CP) (one woman; mean age: 26.3 years; range: 22–31 years) participated in this study….
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Disarming a molecular brake: cAMP-responsive element modulator deletion supercharges CAR-NK cells
In a recent study published in Nature, Rafei and colleagues identified the transcription factor cAMP responsive element modulator (CREM) as an important regulator in natural killer (NK) cells that…
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Biomechanical analysis reveals hormonal crosstalk in inflorescence bending of cut stock flower
Lewis M, Stock M, Black B, Drost D. Stock cut flower production in Utah (2022).
Hartmann, F. P., Decourteix, M. & Moulia, B. Curvature in plants. Curr. Biol. 34(20), R991–R996 (2024).
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Collaborative filtering models an experimental and detailed comparative study
Here, we comprehensively discuss the theoretical background of the selected collaborative filtering methods. We have also highlighted the advantages and disadvantages of each of the methods in Table 1.
We carefully choose the approaches for our…
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Generalizing machine learning models from clinical free text
Clinical free text preprocessing and institutional pairwise analyses
The final dataset consisted of 1,607,393 procedures: 44 institutions covering 48 distinct anesthesiology CPT codes (From 3,566,343 procedures, 432,039 were removed due to missing…
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