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  • A graph homomorphism approach for unraveling histories of metastatic cancers and viral outbreaks under evolutionary constraints

    A graph homomorphism approach for unraveling histories of metastatic cancers and viral outbreaks under evolutionary constraints

    As the research was limited to computational methods, ethical approval from institutional boards was not applicable.

    Basic definitions

    Throughout this paper, we consider a pair of trees: a phylogenetic tree and a migration tree. For clarity, we…

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  • The antitumor effect of tlr4 inhibition in head and neck cancer cell lines

    The antitumor effect of tlr4 inhibition in head and neck cancer cell lines

    Cell culture

    Four HNC cell lines were used in this study: SCC78 (UPCI: SCC078) (RRID: CVCL_C044), a TP53-mutated and HPV-negative, floor of mouth squamous cell carcinoma cell line from a male patient with a history of alcohol and nonsmoker; SCC143…

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  • Deepath-MSI: a clinic-ready deep learning model for microsatellite instability detection in colorectal cancer using whole-slide imaging

    Deepath-MSI: a clinic-ready deep learning model for microsatellite instability detection in colorectal cancer using whole-slide imaging

    Cohort description

    In this multicenter retrospective study, we collected H&E-stained slides from formalin-fixed paraffin-embedded tissue sample obtained from seven independent CRC patient cohorts. Six of seven cohorts were derived from five…

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  • Cross-talk between dopamine and noradrenaline modulates glutamatergic transmission in the deep cerebellar nuclei

    Cross-talk between dopamine and noradrenaline modulates glutamatergic transmission in the deep cerebellar nuclei

  • Nieoullon, A., Cheramy, A. & Glowinski, J. Release of dopamine in both caudate nuclei and both substantia nigrae in response to unilateral stimulation of cerebellar nuclei in the cat. Brain Res. 148, 143–152 (1978).

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  • Species-specific retention vs. recovery of coral thermal tolerance following nursery propagation

    Species-specific retention vs. recovery of coral thermal tolerance following nursery propagation

  • Roberts, C. M. et al. Marine biodiversity hotspots and conservation priorities for tropical reefs. Science 295, 1280–1284 (2002).

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  • Spalding, M. et al. Mapping the global…

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