The promise and challenges of psychedelic-assisted therapy: lessons from Canada’s Special Access Program
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The promise and challenges of psychedelic-assisted therapy: lessons from Canada’s Special Access Program
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Evolutionary unpredictability in cancer model systems
Assumptions underlying in silico modeling
Here, we simulated a synthetic model for tumorigenesis, incorporating some of the basic assumptions of the somatic mutation theory. It remains to be seen whether DNA damage-driven neutral or Darwinian…
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Senescent macrophages induce ferroptosis in skeletal muscle and accelerate osteoarthritis-related muscle atrophy
Ethics statement
All animal experiments were approved by the Institutional Animal Care and Use Committee of Daping Hospital in Chongqing, China, and conducted in accordance with standard guidelines. Human study was conducted according to the…
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Acute neuronal cell death and neuroinflammation per se do not trigger secondary autoimmune encephalitis in mice
Mice
All animal experiments were approved by the local animal care and use committee (LAVES, Niedersaechsisches Landesamt für Verbraucherschutz und Lebensmittelsicherheit, Oldenburg, Germany; license number 33.19-42502-04-18/2803) in accordance…
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Vascular collapse leads to muscle wasting in cancer cachexia
De Palma, M. & Hanahan, D. Nat. Cancer 5, 827–843 (2024).
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Hudlicka, O., Brown, M. & Egginton, S. Physiol. Rev. 72, 369–417 (1992).
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Defactinib with avutometinib in patients with solid tumors: the phase 1 FRAME trial
Competing interests
S.B. has received honoraria for consulting and/or advisory board work from AbbVie, AstraZeneca, BioNTech, Eisai, Gilead, GlaxoSmithKline, Grey Wolf Therapeutics, Immunogen, Incyte, ITM…
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PARP inhibitor-induced anti-tumour chemokine response is suppressed by dipeptidyl peptidase 4 (DPP4) in ovarian cancer
Mirza MR, Coleman RL, González-Martín A, Moore KN, Colombo N, Ray-Coquard I, et al. The forefront of ovarian cancer therapy: update on PARP inhibitors. Ann Oncol. 2020;31:1148–59.
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Author Correction: Global implementation and evaluation of atrial fibrillation screening in the past two decades – a narrative review
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
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Astronomy as a strategic driver for sustainable development
Astronomy as a strategic driver for sustainable development
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Synthesis, characterization and cytotoxic evaluation of metal complexes derived from new N′-(2-cyanoacetyl)isonicotinohydrazide
The N’-(2-cyanoacetyl)isonicotinohydrazide (H2L) elemental analyses indicated that it had C9H8N4O2 formula, whereas its complexes were 1:1 (M: L) stoichiometry and were soluble only in DMF and DMSO. The complexes were non-electrolytic, where…
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