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  • Changes in mitochondrial thymidine metabolism and mtDNA copy number during induced pluripotency

    Changes in mitochondrial thymidine metabolism and mtDNA copy number during induced pluripotency

    This study revealed that a decrease in mtDNA copy number, which is crucial for the transition from OXPHOS-driven metabolism to aerobic glycolysis, is necessary for somatic cells to acquire and maintain pluripotency while undergoing stochastic…

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  • Profound phenotypic deficiencies in mature blood and bone marrow progenitor dendritic cells in chronic lymphocytic leukemia patients

    Profound phenotypic deficiencies in mature blood and bone marrow progenitor dendritic cells in chronic lymphocytic leukemia patients

  • Siegel RL, Giaquinto AN, Jemal A. Cancer statistics, 2024. CA Cancer J Clin. 2024;74:12–49.

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  • Kipps TJ, Stevenson FK, Wu CJ, Croce CM, Packham G, Wierda WG, et al….

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  • Immune impacts of fire smoke exposure

    Immune impacts of fire smoke exposure

  • Wu, Y. et al. Synergistic aircraft and ground observations of transported wildfire smoke and its impact on air quality in New York City during the summer 2018 LISTOS campaign. Sci. Total Environ. 773, 145030 (2021).

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  • An imaging spectrometer for a 4 m solar telescope

    An imaging spectrometer for a 4 m solar telescope

    An imaging spectrometer for a 4 m solar telescope

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  • A new myeloid cell migration route

    Microglia are the resident immune cells of the brain. However, under certain circumstances, other myeloid cells — including bone marrow-derived myeloid cells — can infiltrate the brain parenchyma. These cells, along with border-associated…

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  • AI-powered fragmentomics of cell-free DNA for early detection of multiple cancers

    AI-powered fragmentomics of cell-free DNA for early detection of multiple cancers

    Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

    This is a summary of: Bao, H. et al. Early detection of multiple cancer types using multidimensional…

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  • Attention-based hybrid deep learning model with CSFOA optimization and G-TverskyUNet3+ for Arabic sign language recognition

    Attention-based hybrid deep learning model with CSFOA optimization and G-TverskyUNet3+ for Arabic sign language recognition

    In this research work, a novel ArSL model is introduced, with the assistance acquired from the AI based approaches and hybrid meta-heuristic optimization model. The overall architecture of the proposed model is shown in Fig. 1.

    Fig. 1

    Overall…

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  • Engineering multi-specific nano-antibodies for cancer immunotherapy

    Engineering multi-specific nano-antibodies for cancer immunotherapy

  • Elgundi, Z., Reslan, M., Cruz, E., Sifniotis, V. & Kayser, V. The state-of-play and future of antibody therapeutics. Adv. Drug Deliv. Rev. 122, 2–19 (2017).

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  • AI driven prediction of early age compressive strength in ultra high performance fiber reinforced concrete

    AI driven prediction of early age compressive strength in ultra high performance fiber reinforced concrete

  • Akeed, M. H. et al. Ultra-high-performance fiber-reinforced concrete. Part I: developments, principles, Raw materials. Case Stud. Constr. Mater. 17, e01290. https://doi.org/10.1016/j.cscm.2022.e01290 (2022).

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