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  • GD2TIF cells as a platform for single-dose and long-term delivery of biologics

    GD2TIF cells as a platform for single-dose and long-term delivery of biologics

    Mice and cell lines

    C57BL/6 mice (000664, Jackson Laboratory), Cas9 transgenic mice (026430, Jackson Laboratory) and ob/ob mice (T001461, GemPharmatech) were maintained under specific pathogen-free conditions at the Laboratory Animal Research…

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  • Proanthocyanidins inhibit CYP1B1 through mixed-type kinetics and stable binding in molecular dynamics simulations

    Proanthocyanidins inhibit CYP1B1 through mixed-type kinetics and stable binding in molecular dynamics simulations

    Inhibitory effect of PA on CYP1B1 activity

    PA exhibited a clear, dose-dependent inhibition of CYP1B1-catalyzed ethoxyresorufin O-deethylation (Fig. 1). Even at low micromolar concentrations, PA significantly suppressed resorufin formation,…

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  • Proving vote correctness in the IVXV internet voting system

    Proving vote correctness in the IVXV internet voting system

    Setting

    Let \(\mathbb {G}_p,\mathbb {G}_q\) be two DLOG-groups such that \(q \ll p\). Let \(b_q\) denote the bit-length of q.

    Let x represent a vote and let \(b_x\) be the maximal bit-length of a vote such that \(2^{b_x} \ll q\). Let ab be two…

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  • The effects of an integrated sports and arts intervention on response joint attention (RJA) eye-movement characteristics in children with mild autism

    The effects of an integrated sports and arts intervention on response joint attention (RJA) eye-movement characteristics in children with mild autism

    Participants

    In this study, from 2024.6 to 2024.12, children with ASD were recruited from an autism association in a city in Anhui Province. Inclusion criteria: aged 6–12 years old, possessing a diagnostic certificate of autism issued by the…

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