Author: admin

Continue Reading

  • Repurposing MDM2 inhibitor RG7388 for TP53-mutant NSCLC: a p53-independent pyroptotic mechanism via ROS/p-p38/NOXA/caspase-3/GSDME axis

    Repurposing MDM2 inhibitor RG7388 for TP53-mutant NSCLC: a p53-independent pyroptotic mechanism via ROS/p-p38/NOXA/caspase-3/GSDME axis

    Cell culture and regents

    Human lung cancer cell lines including HCC827, NCI-H23, PC9, NCI-H1975, NCI-H3122, NCI-H2087, Calu-1, Calu-3, NCI-H1299, NCI-H358, NCI-H460 and A549 were obtained from ZQXZBIO, Shanghai, China. For lentivirus package,…

    Continue Reading

  • Community nudges: why we need tools for turning on the we-mode to tackle problems that concern all of us

    Community nudges: why we need tools for turning on the we-mode to tackle problems that concern all of us

  • Agostini M, Van Zomeren M (2021) Toward a comprehensive and potentially cross-cultural model of why people engage in collective action: a quantitative research synthesis of four motivations and structural constraints. Psychol Bull 147:667–700.

  • Continue Reading

  • Battery-free and self-propelled bionic microneedle system for chemically controlled on‐demand drug delivery

    Battery-free and self-propelled bionic microneedle system for chemically controlled on‐demand drug delivery

    System overview

    This work introduces a streamlined BSBMs, engineered for self-powered and on-demand controlled drug delivery without the need for external activation and pumping equipment. The BSBMs is inspired by the venom injection mechanism of…

    Continue Reading

  • Estimating the impact of the Russian invasion on the displacement of graduating high school students in Ukraine

    Estimating the impact of the Russian invasion on the displacement of graduating high school students in Ukraine

    Data source

    The primary data source for this research is standardized exam outcomes used for higher education admissions, provided by the Ukrainian Center for Educational Quality Assessment (UCEQA), which is under the management of the Ministry of…

    Continue Reading

  • Sanitation-related withholding and suppression among women in urban Uganda and India

    Sanitation-related withholding and suppression among women in urban Uganda and India

    Ethics

    Study activities were reviewed and approved by institutional review boards at Emory University, USA (IRB no. 00110271), Azim Premji University, India (reference no. 2019/SOD/Faculty/5.1) and Makerere University, Uganda (reference no….

    Continue Reading

  • Reframing how we talk about ‘energy poverty’

    Reframing how we talk about ‘energy poverty’

    Continue Reading