Department of HPB Surgery and Liver Transplantation, UMCG Comprehensive Transplant Center, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands
Otto B. van Leeuwen & Vincent E. de Meijer
Department of HPB and…
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Integration of MRI radiomics and germline genetics to predict the IDH mutation status of gliomas
An overview of the study design and analysis is provided in Fig. 1. Demographic and clinical characteristics of study participants from The Cancer Genome Atlas (TCGA) stratified by availablity of genotyping and radiomic data is provided in Table
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Comment on: “Diagnostic accuracy of optic nerve OCT and ultrasound in a large paediatric cohort referred with suspected papilloedema and very low rates of raised ICP”
Ambrose C, Graham K, Hamilton R, Houtman AC. Diagnostic accuracy of optic nerve OCT and ultrasound in a large paediatric cohort referred with suspected papilloedema and very low rates of raised ICP. Eye. 2025.
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Acupuncture to reduce nocturia in survivors of prostate cancer
The efficacy of acupuncture to ameliorate nocturia in survivors of prostate cancer was assessed in a pilot randomized clinical trial (NOCTURNAL) conducted at Memorial Sloan Kettering Cancer Center, and the results were published in JAMA…
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Can shifting attention to accuracy reduce misinformation on social media? A replication and extension in China
Purpose of the study
The purpose of Study 1 was to test whether there was a disconnect between accuracy judgments and sharing intentions. The key concept in analyzing this problem is truth discernment, defined as the difference in accuracy…
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High tumor expression of CTLA4 identifies lymph node-negative basal-like breast cancer patients with excellent prognosis
Patient selection and characteristics
We have previously determined the PAM50 subtypes for tumor samples from 666 patients in the Oslo1 study33. Samples from 71 patients were classified as basal-like. Using the nCounter PanCancer Immune Profiling…
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The New Clinical Investigation exclusivity: a substantial source of monopoly time for brand drugs
Drug Price Competition and Patent Term Restoration Act of 1984, Pub. L. No. 98-417, 98 Stat. 1585.
21 U.S.C. § 355(j).
Feldman, R. & Frondorf, E. Drug Wars: How Big Pharma Raises Prices and Keeps Generics Off The Market 21–22, 28–29, 31…
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Quantum computing in surgery and urology — taking a quantum leap
P.D. is supported by the Engineering and Physical Sciences Research Council (EPSRC, grant number EP/Y009800/1), through funding from Responsible AI UK (RAI UK). He also acknowledges funding from the Trustworthy Autonomous Systems (TAS) Hub, the…
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Changes in cardiorespiratory status after transcatheter patent ductus arteriosus closure
This study evaluated the short-term cardiorespiratory outcomes of neonates who underwent transcatheter PDA closure (TCPC), focusing on respiratory risk factors for post-transcatheter cardiorespiratory syndrome (PTCS). Based on RSS differences in…
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Differential analysis of the impact of adopting outsourced machinery services on land transfer between contracted and outsourced land-holding
Baseline regression results
Table 2 reports the impact of adopting outsourced machinery services on outgoing (trans-out) and incoming (trans-in) land transfers for contracted land-holding. Models (1) and (4) present results with only explanatory…
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