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SEER [Internet]. [cited 2024 Apr 11]. Female Breast Cancer Subtypes – Cancer Stat Facts. Available from: https://seer.cancer.gov/statfacts/html/breast-subtypes.html.
Burstein HJ. Systemic therapy for estrogen receptor-positive, HER2-negative…
The variability of the integrated 6.668 GHz CH3OH maser flux during this flare is illustrated in Fig. 1. After the 6.668 GHz CH3OH maser in G36 reached its peak flux density on October 14, 202210, an extensive monitoring…
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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
T cell-based immunotherapies, such as chimeric antigen receptor (CAR) T cells, have transformed cancer treatments; however, their success has been limited to subsets of patients owing to the scarcity of truly tumour-specific antigens. Currently…
Observations of protoplanetary disks indicate that there can be several hundred Earth masses of pebbles embedded in each gas disk1. These pebbles vanish after a few million years, probably due to radial drift and planetesimal formation outside…
Although translation is highly processive, ribosomes stall when they are defective or encounter damaged mRNAs. Stalled ribosomes collide with other ribosomes, leading to non-conventional splitting that leaves a large (60S) subunit with an…
Obligate mobile element guided activity is a class of RNA-guided nucleases such as IscB, the ancestor of Cas9. IscB has been used for genome editing, owing to its small size and large structured guiding RNA (ωRNA). Genome editors with improved…
The ability of metazoan cells to remain attuned to challenging environmental cues such as temperature, osmotic and chemical stresses is essential for developmental resilience. To do so, cells use molecular pathways for stress response signaling….
“Acquisition of somatic mutations coupled with multiple environmental factors contribute to the expansion of the CHIP clones. Higher levels of CHIP are observed in autoimmune, inflammatory, and in some instances of chronic intestinal…