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This is a summary of: Hope, H. C. et al. Age-associated nicotinamide adenine dinucleotide decline drives…
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Ultrafast all-optical generation of pure spin and valley currents
Pure spin current
We first consider the generation by laser light of a pure spin current in WSe2; to this end we employ a minimal tight-binding model and evolution according to the von Neumann equation of motion we use a decoherence time T226,27,
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Stable isotopes unveil ocean transport of legacy mercury into Arctic food webs
Spatial trends in sources and pathways
In the peat profiles, Hg stable isotopes reveal significant spatial differences in δ202Hg signatures between Central West Greenland (Qeqertarsuaq) and Northeast Greenland (Zackenberg) (Fig. 1a, b;…
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Transcription factor binding divergence drives transcriptional and phenotypic variation in maize
Kim, S. & Wysocka, J. Deciphering the multi-scale, quantitative cis-regulatory code. Mol. Cell 83, 373–392 (2023).
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Rodriguez-Leal, D., Lemmon, Z. H., Man,…
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Contrasting and comparing the efficacy of mobility-targeted interventions on airborne and vector-borne diseases
Effect of mobility-interventions in Cali, Colombia
In Fig. 1a, we present a map of Cali, highlighting hotspot (suburbs) in dark (light) blue. For reference, the population density distribution across communes is provided in Supplementary Fig. 2….
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Increased matrix stiffness promotes fibrogenesis of hepatic stellate cells through AP-1-induced chromatin priming
Wells, R. G. The role of matrix stiffness in regulating cell behavior. Hepatology 47, 1394–1400 (2008).
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Engler, A. J., Sen, S., Sweeney, H. L. & Discher,…
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Strain-tuning for superconductivity in La3Ni2O7 thin films
Epitaxial thin film
We fabricated La3Ni2O7 thin films on three substrates using pulsed-laser deposition (see Methods for details). To tune the strain, we selected SrTiO3 (001) with (aSTO = 3.905 Å), NdGaO3 (001)pc (aNGO = 3.855 Å)…
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Longitudinal assessment of the association between pesticide exposure and lifestyle with Parkinson’s disease motor severity
Investigating the impact of environmental and lifestyle factors beyond the onset of PD is of great importance, as there is increasing evidence that those factors affect the disease course. Thus far, there has been no longitudinal study on the…
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Cell-state-specific enhancer design in hematopoiesis
During cellular differentiation, the activity of transcription factors (TFs) changes to regulate the expression patterns of lineage-specific genes. However, it remains unclear how enhancers can transform the activity of an identical set of TFs…
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T-DXd effective as second-line therapy in G/GEJ cancers
Patients with HER2-positive (HER2+) metastatic gastric or gastroesophageal junction (G/GEJ) adenocarcinoma with disease progression on first-line therapy have various treatment options available, although the most-effective agent remains…
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