To acquire a comprehensive clinical phenotype, participants completed several cognitive and clinical scales. Compared to HCs, the MUD group showed elevated symptoms of anxiety and depression, higher impulsivity, reduced cognitive performance…
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The spatial layout of antagonistic brain regions is explicable based on geometric principles
We first demonstrate the utility of kriging as a technique for explaining the spatial distribution of increases and decreases in brain activity using group average BOLD activity from the Human Connectome Project15. We took a single group-averaged…
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Landscape control for cell fate transitions
Stochastic differential equations (SDEs) for gene regulatory networks (GRNs)
In this study, we will demonstrate the superiority of our LC method, integrated with the identification of key gene targets, for achieving stable-state control across…
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Comprehensive Dataset for Polychaetes in the IPC: Species Distribution, DNA Barcodes, and Functional Traits
The dataset can be found in a figshare repository (Weng et al.22, and are licensed under CC BY.
The database, which includes three main components (occurrence records, DNA barcode data and functional traits), is organized into three distinct files…
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Changes in epistatic green-beard alleles induce domain shift in hypostatic rock-paper-scissors-like green-beard competition
Sah, G. P. & Wall, D. Kin recognition and outer membrane exchange (OME) in myxobacteria. Curr. Opin. Microbiol. 56, 81–88 (2020).
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Vassallo, C. N….
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Genome-wide identification and analysis of recurring patterns of epigenetic variation across individuals
Systematic genomic annotation of chromatin variation across individuals
We applied a stacked version of the ChromHMM framework to learn a ChromHMM model where all histone modifications in all individuals are used as features21,22,23. We used…
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Costs of photosynthesis and cellular remodeling in trophic transitions of the unicellular red alga Galdieria partita
Algal strains and culture conditions
Galdieria partita (NBRC 102759; Biological Resource Center, National Institute of Technology and Evaluation; https://www.nite.go.jp/en/nbrc/) was used throughout this study. For genetic modification, the haploid…
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Neoadjuvant therapy-induced immune dynamics and myeloid-associated resistance in advanced head and neck cancer
Baseline immune profiles stratify therapeutic effects and immune cell densities following combination therapy with paclitaxel, carboplatin, and cetuximab
To elucidate the alterations in the tumor-immune microenvironment in response to chemotherapy…
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Observational social learning of “know-how” and “know-what” in wild orangutans: evidence from nest-building skill acquisition
Prasetyo, D. et al. Nest building in orangutans. in Orangutans; Geographic Variation in Behavioral Ecology and Conservation (eds Wich, S. A., Utami-Atmoko, S. S., Mitra Setia, T. & van Schaik, C. P.) 269–277 (Oxford University Press, 2009).
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Hydrazone-based photocages for precise sub-organelle visualization and drug release
Design of hydrazone-based photocages
These photocages designed were shown in Fig.1a. We have chosen different aldehydes of dyes and phenylhydrazines to construct five series of photocages (PC1-2, FY1-4, CM1-3, TP1-2, BW1-3), which were synthesized…
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