Quality controls and data integrity
Renerva, Inc., the sponsor of the studies presented herein, operates under the guidance and controls of ISO 13485 Medical devices—Quality management systems—Requirements for regulatory purposes. As such,…
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Nanoscale confinement of phonon flow and heat transport
Warzoha, R. J. et al. Applications and impacts of nanoscale thermal transport in electronics packaging. J. Electron. Packag. Trans. ASME 143, 020804 (2021).
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Choi, S., Heller, E. R.,…
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A new LRRK2 variant in a family with Parkinson’s disease affects binding to RAB8A
Clinical and neuropathological exams
We studied a Spanish Caucasian family with a known history of Parkinsonism in five members from three generations, segregating in an autosomal dominant manner. Neurological examination was performed in the…
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Data-driven stability analysis of complex systems with higher-order interactions
Data-driven investigation of stability in nonlinear dynamical systems with tipping elements
To validate our approach, we simulate time series from two- and ten-dimensional nonlinear systems with known dynamics and show that the estimated…
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Merkel cell stimulation in fear and sensory signaling
Fenster RJ, Lebois LAM, Ressler KJ, Suh J. Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man. Nat Rev Neurosci. 2018;19:535–51.
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High fat diet induces gastric production of fibroblast growth factor 23 (FGF23)
Animal model and maintenance
The animal experiments in this study were approved by the state of Baden-Württemberg, Germany, and were in accordance with the federal law for welfare of animals.
Male adult mice (B6129PF2/J background, JAX Stock…
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Investigation of brain white matter and social cognition in schizophrenia and schizotypal personality disorder using neurite orientation dispersion and density imaging
Pulay AJ, Stinson FS, Dawson DA, Goldstein RB, Chou SP, Huang B, et al. Prevalence, correlates, disability, and comorbidity of DSM-IV schizotypal personality disorder: results from the wave 2 national epidemiologic survey on alcohol and related…
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Delayed rewards weaken human goal directed actions
Participants completed an action-outcome or instrumental task in which they played the role of stockbrokers, making investments in stocks from two fictitious companies (“Initech” and “Globex”) in two different cities or contexts (Paris…
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PCM1 orchestrates centrosomal and flagellar protein transport to promote sperm maturation
Inclusion of clinical patients and testicular biopsy collection
Clinical patients with NOA, characterized by severe spermatogenic arrest and no testicular spermatids and epididymal sperm, were identified by visual microscopy and a…
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Want a worry-free trip? Seeking the optimal travel paradigm in view of public-to-individual risk perception
The application of the IRP metric enables us to delve into the correlation between tourists’ risk perception and their choice of travel paradigms, offering profound insights into how risk perception influences their travel preferences.
What is…
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