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  • Mouse liver assembloids model periportal architecture and biliary fibrosis

    Mouse liver assembloids model periportal architecture and biliary fibrosis

    Modelling liver disease requires in vitro systems that replicate disease progression1,2. Current tissue-derived organoids fail to reproduce the complex cellular composition and tissue architecture observed in vivo3. Here, we describe a…

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  • Research on durability of underground lining structures using damage theory

    Research on durability of underground lining structures using damage theory

    Meso-damage model for concrete

    In the last decades, many meso-mechanical models have been proposed by researchers to study the damage and fracture processes in concrete. Among these models, the most typical and representative ones are the Gurson…

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  • Discovery of the α-emitting isotope 210Pa

    Discovery of the α-emitting isotope 210Pa

    Based on the obtained results, the observed α decay of 210Pa can be assigned as the ground-state to ground-state transition. The α-particle energy and half-life allow us to extend the α-decay systematics and provide a rigorous test of nuclear…

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  • Genome-wide investigation of cytokinin oxidase/dehydrogenase (CKX) family genes in Brassica juncea with an emphasis on yield-influencing CKX

    Genome-wide investigation of cytokinin oxidase/dehydrogenase (CKX) family genes in Brassica juncea with an emphasis on yield-influencing CKX

    Characterization of BjCKX gene family

    The nucleotide sequence alignment of the 23 CKX genes known in B. juncea var. Tumida with the whole genome sequence of B. juncea cv. Varuna by using the BLASTn program of BLASTN 2.13.0 + resulted in a…

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  • Association between triglyceride glucose index and organ involvement in patients with systemic sclerosis

    Association between triglyceride glucose index and organ involvement in patients with systemic sclerosis

    Characteristics of the study participants

    Mean TyG index was higher in SSc patients versus controls (8.50 \(\:\pm\:\) 0.45 vs. 8.33 \(\:\pm\:\) 0.43; P = 0.006) (Table 1). SSc patients with renal involvement or CVD had higher TyG index than…

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  • Optimising the mechanical properties of concrete for non-structural applications through partial replacement of fine aggregates with wastewater sludge

    Optimising the mechanical properties of concrete for non-structural applications through partial replacement of fine aggregates with wastewater sludge

    Physical and chemical properties of wastewater sludges from various WWTPs

    The physical characteristics of the sludges from the Mankweng, Polokwane, and Seshego WWTPs are summarised in Table 2. The dust content, compacted bulk density, relative…

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  • Controlling salt deposition patterns using engineered substrates and thermal gradients

    Controlling salt deposition patterns using engineered substrates and thermal gradients

  • Deegan, R. D. et al. Contact line deposits in an evaporating drop. Phys. Rev. E 62, 756–765 (2000).

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  • Erbil, H. Y. Evaporation of pure liquid sessile and…

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  • Structural basis of GluK2 kainate receptor activation by a partial agonist

    Structural basis of GluK2 kainate receptor activation by a partial agonist

  • Hansen, K. B. et al. Structure, function, and pharmacology of glutamate receptor ion channels. Pharm. Rev. 73, 298–487 (2021).

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  • Lerma, J. Roles…

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  • In vitro and in silico evaluation of fluorinated diphenylamine chalcone derivatives as potential antimalarial and anticancer agents

    In vitro and in silico evaluation of fluorinated diphenylamine chalcone derivatives as potential antimalarial and anticancer agents

    Chemistry

    The chalcones were synthesized by reacting substituted aldehydes with a diphenylamine ketone derivative, specifically 1-(3-((3,4-difluorophenyl)amino)phenyl)ethan-1-one,(RM) in the presence of potassium hydroxide (KOH) as the base and…

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