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  • Structural basis of GluK2 kainate receptor activation by a partial agonist

    Structural basis of GluK2 kainate receptor activation by a partial agonist

  • Hansen, K. B. et al. Structure, function, and pharmacology of glutamate receptor ion channels. Pharm. Rev. 73, 298–487 (2021).

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  • Lerma, J. Roles…

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  • In vitro and in silico evaluation of fluorinated diphenylamine chalcone derivatives as potential antimalarial and anticancer agents

    In vitro and in silico evaluation of fluorinated diphenylamine chalcone derivatives as potential antimalarial and anticancer agents

    Chemistry

    The chalcones were synthesized by reacting substituted aldehydes with a diphenylamine ketone derivative, specifically 1-(3-((3,4-difluorophenyl)amino)phenyl)ethan-1-one,(RM) in the presence of potassium hydroxide (KOH) as the base and…

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  • Platelet aggregation elicits FasL expression and hepatocyte apoptosis in sinusoidal obstruction syndrome

    Platelet aggregation elicits FasL expression and hepatocyte apoptosis in sinusoidal obstruction syndrome

    Monocrotaline (MCT) was purchased from FUJIFILM Wako Pure Chemical Corporation (Osaka, Japan). To prepare the MCT solution, the powder was dissolved in 1.0 N HCl and then adjusted to pH 7.4 with 0.5 N NaOH. A Fas/FasL antagonist, Kp7-6, was…

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  • Load demand forecasting in air conditioning a rotor Hopfield neural network approach optimized by a new optimization algorithm

    Load demand forecasting in air conditioning a rotor Hopfield neural network approach optimized by a new optimization algorithm

    The inspiration for the suggested algorithm has been, first, presented in this section. After that, more detail was given by the use of the mathematical model, and the algorithm’s operation has been demonstrated using a basic cost function.

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