To evaluate the effectiveness of our proposed federated learning framework for speech-based Parkinson’s disease detection, we utilized five multilingual datasets, incorporating Spanish, Italian, Chinese, Czech, and English speech samples. These…
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The power of patient engagement at Peace and Love Hospitals in Ghana
In today’s evolving healthcare landscape, patient engagement has emerged as a cornerstone of delivering high-quality care. By incorporating patient voices throughout the care life cycle, including survivorship, healthcare systems are fostering…
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Establishing predictive machine learning models for drug responses in patient derived cell culture
To develop an efficient methodology for predicting drug responses in patient-derived cell lines we performed a few initial probing experiments using a dedicated validation set from the GDSC1 dataset (Fig. 2). These provided the foundation for…
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Vitamin D: recent advances, associated factors, and its role in combating non-communicable diseases
Liss, Y. & Frishman, W. H. Vitamin D: A cardioprotective agent?. Cardiol. Rev. 20, 038–44 (2012).
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Gebhardt S. E., TR, EJ, LL, & HJ. Estimation of the Vitamin D Content of Foods…
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The brain works at more than 10 bits per second
A recent article makes a claim with far-reaching implications for neuroscience, technology, and society: that the human brain is subject to an information processing ‘speed limit’ of 10 bits per second. Although this speed limit appears to…
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Detection and characterization of rare variants in NOTCH2NLC causing false negative molecular diagnosis through long-read sequencing
Wu W, Yu J, Qian X, Wang X, Xu Y, Wang Z, et al. Intermediate-length CGG repeat expansion in NOTCH2NLC is associated with pathologically confirmed Alzheimer’s disease. Neurobiol Aging. 2022;120:189–95.
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Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis
ER–mitochondria contacts rapidly expand during ferroptosis
To assess the dynamics of EMCS remodelling induced by lipid-ROS in real time, we first validated the induction of ferroptosis in our cellular model. We used the RAS-selective lethal…
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PET-based tracking of CAR T cells and viral gene transfer using a cell surface reporter that binds to lanthanide complexes
Cloning of plasmids
Construction of plasmids, for example, for the production of retrovirus- and AAV-based vectors, was accomplished by standard cloning techniques. Sequence maps for DTPA-R and Colchi-R can be found in the Supplementary…
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Education of healthcare professionals to improve guideline adherence in atrial fibrillation: the STEEER-AF cluster-randomized clinical trial
Competing interests
All principal authors have completed the International Committee of Medical Journal Editors (ICMJE) uniform disclosure form. D.K. declares support for the present manuscript as…
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