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  • Stroma content in triple-negative breast cancer spheroid models regulates penetration and efficacy of tumor-targeting Salmonella typhimurium

    Stroma content in triple-negative breast cancer spheroid models regulates penetration and efficacy of tumor-targeting Salmonella typhimurium

    Mammalian cell culture

    Triple-negative murine mammary carcinoma (4T1, ATCC CRL − 2539) and murine mammary cancer-associated fibroblasts (mCAFs)37 were used for the experiments. The 4T1 cells were grown in Roswell Park Memorial Institute 1640…

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  • On-farm resource-use efficiency in China: overall rebounding trends and region-specific enhancement opportunities

    On-farm resource-use efficiency in China: overall rebounding trends and region-specific enhancement opportunities

    Description of the framework

    We followed the approach taken by Pellegrini and Fernández (Pellegrini and Fernández, 2018) to assess on-farm energy-use efficiency, as measured by the output-input ratio. To do so, we constructed an output-input…

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  • Sea dragon metabolome and lipidome unveil bioactive functional food candidates with sepsis therapeutic activities

    Sea dragon metabolome and lipidome unveil bioactive functional food candidates with sepsis therapeutic activities

    Comprehensive analysis of metabolites in sea dragons

    For metabolomics, the total ion flow chromatograms (TIC) in positive and negative ion modes are shown in Fig. S1, respectively. As shown in Figs. 1a and 2b, a total of 2264 metabolites were…

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  • The CRP–albumin–lymphocyte index provides enhanced prognostic value in liver cancer compared to the TNM staging system

    The CRP–albumin–lymphocyte index provides enhanced prognostic value in liver cancer compared to the TNM staging system

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  • Villanueva, A. Hepatocellular carcinoma. N. Engl. J. Med. 380(15), 1450–1462…

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  • Investors matter when prices are dispersed: the effects of investor activities on housing price dispersion

    Investors matter when prices are dispersed: the effects of investor activities on housing price dispersion

    Data and preliminary description

    Three essential characteristics of Hong Kong’s private housing market (HKPHM) make it a compelling and appropriate setting for studying the relationship between investor activities and housing price dispersion….

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  • Machine learning-based MRI radiomics predict IL18 expression and overall survival of low-grade glioma patients

    Machine learning-based MRI radiomics predict IL18 expression and overall survival of low-grade glioma patients

  • Sung, H. et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 71, 209–249 (2021).

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  • ELD1 mediates photoperiodic flowering via OsCCA1 alternative splicing and interacts with phytochrome signaling in rice

    ELD1 mediates photoperiodic flowering via OsCCA1 alternative splicing and interacts with phytochrome signaling in rice

    ELD1 negatively regulates flowering time in rice under long-day conditions

    To explore the regulatory factors influencing flowering time in rice, we isolated the early flowering at long day 1 (eld1) mutant from an ethyl…

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  • Impact of fludarabine dose on outcome after allo-HSCT with reduced intensity conditioning for older patients with AML

    Impact of fludarabine dose on outcome after allo-HSCT with reduced intensity conditioning for older patients with AML

  • Dohner H, Wei AH, Appelbaum FR, Craddock C, DiNardo CD, Dombret H, et al. Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN. Blood. 2022;140:1345–77.

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  • Genomic evidence for flies as carriers of zoonotic pathogens on dairy farms

    Genomic evidence for flies as carriers of zoonotic pathogens on dairy farms

  • Jones, K. E. et al. Global trends in emerging infectious diseases. Nature 451, 990–993 (2008).

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  • Guo, Y. et al. Association of common…

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