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Exploring the role of infected keratinocytes during rabies virus infection
Hampson, K. et al. Estimating the global burden of endemic canine rabies. PLoS Negl. Trop. Dis. 9, e0003709 (2015).
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Wallace, R. M., Undurraga, E….
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Murine astrovirus infection course and antibody response in different mouse strains
Primary sites of MuAstV replication and virus shedding
In two experimental parts, a short-term and a long-term experiment, mice of three immunocompetent strains and one immunodeficient strain, that is, CD1, C57BL/6, BALB/c and NOD scid gamma…
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Lipid nanoparticle screening in nonhuman primates with minimal loss of life
mRNA synthesis
The template for in vitro transcription (IVT) of glycosylphosphatidylinositol-aVHH was purchased from Integrated DNA Technologies. The sequences (Supplementary Table 1) were codon-optimized for mouse (primary species) and human…
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DCPS is a synthetic lethal therapeutic target in acute myeloid leukemia expressing low levels of FHIT
For a therapy to be successful in the clinic, efficacy and safety are paramount. The identification of viable biomarkers is also advantageous for increasing treatment success. Recently, the pyrophosphatase DCPS (Decapping scavenger enzyme) was…
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Smart closed-loop drug delivery systems
Mujeeb-U-Rahman, M., Nazari, M. H., Sencan, M. & Antwerp, W. V. A novel needle-injectable millimeter scale wireless electrochemical glucose sensing platform for artificial pancreas applications. Sci. Rep. 9, 17421 (2019).
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A misplaced microbiome | Nature Reviews Microbiology
Faecal microbiota transplantation (FMT) is a promising procedure to restore dysbiosis of the gut microbiota. However, the efficacy and off-target effects of FMT are not yet well established. The gut microbiota exhibits distinct regional…
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Daily electric field treatment improves functional outcomes after thoracic contusion spinal cord injury in rats
Implant fabrication
The implants were fabricated in the cleanroom facility at the University of Freiburg (RSC, ISO 4, according to ISO 14644-1) following similar fabrication steps as in previous works49,57. First, polyimide (U-Varnish-S, UBE…
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A reality check | Nature Reviews Neuroscience
Mental imagery, which involves the internal simulation of scenarios or stimuli that are not physically present, engages many of the brain systems involved in perception of the external world. Dijkstra et al. now identify a neural mechanism that…
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