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  • Harnessing protein language model for structure-based discovery of highly efficient and robust PET hydrolases

    Harnessing protein language model for structure-based discovery of highly efficient and robust PET hydrolases

    Structure search

    In the structural search step, we utilized the default setting of the FoldSeek server website (https://search.foldseek.com/search). The structure of IsPETase (PDB: 5XFY) is selected as the only query protein for the FoldSeek…

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  • Influence of lifestyle risk factors and genetic predisposition on metabolic syndrome risk in Korean adults

    Influence of lifestyle risk factors and genetic predisposition on metabolic syndrome risk in Korean adults

    This study explored the association between PRSMetS and the risk of MetS and investigated the impact of lifestyle risk factors on MetS risk in the Korean general population. The main findings were as follows: (i) individuals with high PRSMetS had…

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  • Investigating the correlation between ultrasonic pulse velocity and compressive strength in polyurethane foam concrete

    Investigating the correlation between ultrasonic pulse velocity and compressive strength in polyurethane foam concrete

    Workability

    Workability measures how easily freshly mixed concrete can be placed, compacted, and finished without segregation or loss of homogeneity. The workability of fresh concrete was evaluated using the slump test, conducted in compliance…

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  • Lactate-related gene signatures predict prognosis and immune profiles in esophageal squamous cell carcinoma

    Lactate-related gene signatures predict prognosis and immune profiles in esophageal squamous cell carcinoma

    Identification of DEGs for ESCC

    After removing batch effects from the three GEO datasets, the expression profiles of ESCC and normal samples were obtained, resulting in a gene count of 3,907 (Fig. 2A, Supplementary Fig. 1A-D). Differential…

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  • Predictive values of neck circumference and TyG index on polycystic ovary syndrome with metabolic syndrome

    Predictive values of neck circumference and TyG index on polycystic ovary syndrome with metabolic syndrome

    Subject baseline characteristics based on PCOS/MetS

    Participants were divided into four groups according to the quartiles of NCs(NC1-NC4). Except for age, significant group differences (all P < 0.05) were observed in: hemodynamic index (SBP,…

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  • Investment strategies for renewable energy technologies and harvesting systems in airport operations using spherical fuzzy MCDM models

    Investment strategies for renewable energy technologies and harvesting systems in airport operations using spherical fuzzy MCDM models

    This study aims to identify the most effective investment strategies for sustainable energy in airport operations by utilizing a robust multi-criteria decision-making (MCDM) methodology. Five key criteria—economic feasibility, environmental…

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  • Cyclic expansion extrusion results in successful consolidation and enhancements in mechanical and physical properties of semi biodegradable Ti-Mg composite implants

    Cyclic expansion extrusion results in successful consolidation and enhancements in mechanical and physical properties of semi biodegradable Ti-Mg composite implants

    XRD analysis

    To evaluate the phases of a typical CEE product, the X-ray Diffraction Spectrometer (XRD) method was utilized. On a polished specimen, using a Philips X’PERT PW3040 diffractometer (40 kV/30 mA) with Cu Ka radiation (k = 0:154059…

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  • The first chromosome-level genome of the lappet moth Trabala vishnou (Lepidoptera: Lasiocampidae)

    The first chromosome-level genome of the lappet moth Trabala vishnou (Lepidoptera: Lasiocampidae)

    Sample collection and genome sequencing

    Adult specimens of T. vishnou (Fig. 1) were collected from Mount Tianchi (34.26°N, 111.84°E; 1000 m), Songxian County, Luoyang Caity, Henan Province, China, in July 2024. The adults were reared in mesh…

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