A “gene silencer” (technically known as small interfering RNA, or siRNA), locally delivered by nanoparticles embedded in an injectable gel produced through 3D printing, can switch off the defective gene responsible for serious rare diseases known…
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Rare cranial disorders: Towards a non-invasive therapy using gene silencing delivered by nanoparticles and 3D printing
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Software engineering: How hybrid delivery systems adapt to real-world challenges
New research into project management in software engineering shows that the most successful systems are not the ones that follow a fixed blueprint from the start, but those that evolve in response to real challenges as projects unfold.
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New model reveals significant energy requirement of rapid fossil fuel phase-out
A substantial “transition energy” is required to phase out fossil fuels in the European Union, a study by Imperial College London has found, revealing that faster transitions demand significantly larger, and potentially disruptive, reallocations…
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Brain-inspired neuromorphic computer uses tiny LEDs to cut AI energy use
German scientists are building a brain-like neuromorphic computer that replaces traditional transistors with microscopic LEDs, in order to significantly reduce the power required to run AI systems.
Known as BRIGHT (Bringing Light to…
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Lack of employee flexibility to attend health care appointments during work hours has knock-on health impacts
Restricted access to health care appointments during typical working hours leads to poorer health-related quality of life, a University of Manchester–led study has found. The research explores how being unable to attend health care appointments…
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Advancing the realization of oral insulin using novel peptide technology
For more than a century, oral insulin has been considered a “dream” therapy for diabetes, hindered by enzymatic degradation in the digestive tract and the absence of a dedicated intestinal transport mechanism. Consequently, many patients must…
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GNSS-only method delivers stable positioning for autonomous vehicles in urban areas
Global navigation satellite systems (GNSS) are vital for positioning autonomous vehicles, buses, drones, and outdoor robots. Yet its accuracy often degrades in dense urban areas due to signal blockage and reflections.
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New drug delivery mechanism could aid breast cancer treatment
In a study published in the Journal of Extracellular Vesicles, scientists from the UF Health Cancer Institute have found a way to make treatment for a notoriously aggressive breast cancer more effective. Using a delivery system that relies on…
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Biologists and engineers follow goopy clues to plant-wilting bacteria
Slippery, drippy goop makes Ralstonia bacteria devastating killers of plants, causing rapid wilting in tomato, potato, and a wide range of other crops, according to new research. The work, published Jan. 22 in Proceedings of the National Academy…
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Glassy dynamics model predicts lipid exchange rates across cell membranes
Biological processes that govern our lives are many, intertwined, and often difficult to understand. They involve countless interactions happening at once—molecules recognizing each other, signals being transmitted, and matter being transported…
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