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  • Characterizing aging-related genetic and physiological determinants of spinal curvature

    Characterizing aging-related genetic and physiological determinants of spinal curvature

    Study population: the UK Biobank

    The UK Biobank (UKBB) recruited 503,000 community-based adult volunteers aged 40-69 from 2006-2010 in 22 study centers across the United Kingdom: England, Wales, and Scotland18. In the current analysis, we evaluate…

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  • How a lack of haptic feedback affects eye-hand coordination and embodiment in virtual reality

    How a lack of haptic feedback affects eye-hand coordination and embodiment in virtual reality

    The object interaction task used in this dataset (Pasta Box Task) was originally used to study eye-hand coordination in the real world31, and has previously been translated into VR using hand-held controllers32. The version of the task used here…

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  • Integrative analysis of multi-omics data and gut microbiota composition reveals prognostic subtypes and predicts immunotherapy response in colorectal cancer using machine learning

    Integrative analysis of multi-omics data and gut microbiota composition reveals prognostic subtypes and predicts immunotherapy response in colorectal cancer using machine learning

  • Morgan, E. et al. Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN. Gut 72 (2), 338–344 (2023).

    PubMed 

    Google Scholar 

  • Chung, D. C. et al. A…

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  • A study on factors shaping innovative work behavior and service innovation performance in government sectors: role of digital leadership and dynamic capabilities

    A study on factors shaping innovative work behavior and service innovation performance in government sectors: role of digital leadership and dynamic capabilities

    Digital leadership

    DL in government can be defined as the ability of public sector leaders to guide and manage the integration of digital technologies into the fabric of government operations to improve efficiency, innovation, and public service…

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  • Integrated bioinformatics identifies ferroptosis biomarkers and therapeutic targets in idiopathic pulmonary arterial hypertension

    Integrated bioinformatics identifies ferroptosis biomarkers and therapeutic targets in idiopathic pulmonary arterial hypertension

    Identification of DE-FRGs from GSE48149

    Of 237 FRGs, 27 DE-FRGs exhibited a significant difference between IPAH and normal samples in GSE48149, with 15 downregulated and 12 upregulated genes (Table 1), visualized using a heatmap (Fig. 1A). The…

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  • Real world efficacy safety and drug survival of secukinumab over 6 years at the largest biological center in Poland

    Real world efficacy safety and drug survival of secukinumab over 6 years at the largest biological center in Poland

    Our study showed efficacy of secukinumab reaching 88.2% after 3 months of therapy and 88.9% after 6 months. In our study, secukinumab proved effective in the assessment after 3 and 6 months regardless of the disease, its form, and the disease…

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  • The role of virtual reality-based cognitive training in enhancing motivation and cognitive functions in individuals with chronic stroke

    The role of virtual reality-based cognitive training in enhancing motivation and cognitive functions in individuals with chronic stroke

    The present study aimed to evaluate the effects of VR rehabilitation on motivation, cognitive function, and emotional state in post-stroke patients compared to conventional cognitive rehabilitation. Indeed, the experimental group demonstrated…

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  • Interplay between large low-recombining regions and pseudo-overdominance in a plant genome

    Interplay between large low-recombining regions and pseudo-overdominance in a plant genome

  • Fisher, R. A. The Genetical Theory of Natural Selection (Clarendon Press, 1930).

  • Kimura, M. The Neutral Theory of Molecular Evolution (Cambridge University Press, 1983).

  • Charlesworth, D. Balancing selection and its effects on sequences in nearby…

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