Hypertrophic Olivary Degeneration (HOD) is a form of transsynaptic degeneration caused by lesions in the dentato-rubro-olivary pathway. It was first described by Oppenheim in 1887 during autopsy. In 1931, Guillain and Mollaret proposed that the…
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Strategic design of a multi-tier database for class A β-lactamase BlaC variants of M. tuberculosis: advancing the fight against antibacterial resistance
Cortoos PJ, De Witte K, Peetermans WE, Simoens S, Laekeman G. Opposing expectations and suboptimal use of a local antibiotic hospital guideline: a qualitative study. J Antimicrob Chemother. 2008;62:189–95.
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Distinguished role of the laser pulse temporal structure on deuteron acceleration
Shaping of a pulse temporally
The SEA laser of ELI-ALPS30 delivers 11 fs, p-polarized pulses to the target, with a temporal contrast exceeding 1011. The temporal shape of a laser pulse can be calculated from the measured spectrum (Fig. 1a) and…
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On-chip Cherenkov radiation tuning in 3.2-14 THz
Design and fabrication
The proposed on-chip free-electron THz source is sketched in Fig. 1a. The HMM in the THz frequency region is constructed by alternating graphene and hBN layers (see Supplementary Information Section S1). On the two sides…
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Development of the generalized ridge estimator for the Poisson-Inverse Gaussian regression model with multicollinearity
The PIG distribution combines two probability distributions: the Poisson and the Inverse Gaussian. Let \(Y\) represent a random variable following a Poisson distribution with a mean of \(\mu \nu\), where \(\nu\) itself follows an Inverse Gaussian…
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MRI and 18F-BPA PET-guided targeting in boron neutron capture therapy
Integration of anatomical and functional imaging
The observed discrepancies between GTVMRI and GTVPET highlight the limitations of relying solely on anatomical imaging for target delineation in BNCT. While MRI provides excellent soft tissue…
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Single-cell transcriptome sequencing reveals tumor stem cells and their molecular characteristics in intrahepatic cholangiocarcinoma
Analysis of the transcriptional states of epithelial and tumor cells in ICC and cell type annotation
To investigate the transcriptional states of individual cells in ICC and normal bile duct tissues, we performed a comprehensive analysis of the…
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Hybrid Bayesian deep learning model for predicting urban heat island intensity in African cities
Performance metrics
To evaluate the predictive performance of the models, the following metrics were utilized:
MAE measures the average magnitude of errors in predictions, without considering their direction as shown in Eq. (10).
$$MAE=\frac{1}{n}…
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