Molecular cloning and AAV production
The original Ribo-STAMP construct consisted of a Tet-On hRPS2–APOBEC lentiviral expression vector, with a human phosphoglycerate kinase (PGK) promoter driving the expression of rtTA and pac, designed for…
Author: admin
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Integrase anchors viral RNA to the HIV-1 capsid interior
Recombinant proteins
The vector pCPH6P-HIV1-IN used for bacterial expression of HIV-1 IN with a cleavable hexahistidine (His6) tag was previously described45. To obtain pCPH6P-SIVtal-IN, the DNA region encoding HIV-1 IN was replaced with a…
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Highly dynamic dural sinuses support meningeal immunity
Coles, J. A., Myburgh, E., Brewer, J. M. & McMenamin, P. G. Where are we? The anatomy of the murine cortical meninges revisited for intravital imaging, immunology, and clearance of waste from the brain. Prog. Neurobiol. 156, 107–148 (2017).
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Deterministic and probabilistic health risk assessment of heavy metals in liquid herbal cough formulations from Western Uganda
Walusansa, A. et al. Herbal medicine used for the treatment of diarrhea and cough in Kampala city, Uganda. Trop. Med. Health. 50, 23. https://doi.org/10.1186/s41182-021-00389-x (2022).
Oryema,…
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Jack Altman joins Benchmark as GP
Jack Altman and Benchmark announced today that he would be joining the firm as a general partner.
This news is a big deal, especially since Altman has been running his own VC firm, Alt Capital, since at least 2024. The fund raised a $150…
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Medtronic earns FDA clearance for Stealth AXiS spinal surgery system
The Stealth AXiS system brings together planning, navigation, and robotics into one platform for spine surgery. | Source: Medtronic
Medtronic PLC last week announced the U.S. Food and Drug Administration has cleared its Stealth AXiS surgical…
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World’s smallest QR code, smaller than bacteria, earns Guinness record
A research team at TU Wien and Cerabyte just shrunk the QR code to an impossible scale.
Their creation measures only 1.98 square micrometers. This makes the code smaller than most bacteria. It is so tiny that only an electron microscope can…
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The outrage over the Enhanced Games ignores the risks many already accept in sport
The Enhanced Games, slated to commence in May 2026, has sparked outrage across the sporting world. This new competition is the first in history to openly permit performance-enhancing drugs, and sporting bodies aren’t happy about it.
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Operando X-rays reveal key aging process in sodium-zinc molten salt batteries
Up to now, it has only been possible to deduce indirectly why high-temperature batteries lose efficiency and durability while in use. For the first time, a team from the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) has now used operando X-ray…
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Is exercise overrated for osteoarthritis? What the latest evidence suggests
The effectiveness of exercise therapy to ease the symptoms of osteoarthritis is likely minimal, short lived, and probably no better than no treatment at all, suggests an overarching (umbrella) systematic review and pooled data analysis of the…
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