How does our DNA store the massive amount of information needed to build a human being? And what happens when it’s stored incorrectly? Jesse Dixon, MD, Ph.D., has spent years studying the way this genome is folded in 3D space—knowing that…
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Does the motion of DNA influence its activity?
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Cosmic predators: How supermassive black holes slow star growth in nearby galaxies
Intense radiation emitted by active supermassive black holes—thought to reside at the center of most, if not all, galaxies—can slow star growth not just in their host galaxy, but also in galaxies millions of light-years away, according to a…
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The tiny tuxedo cat who became a naval hero
One day in March of 1948, George Hickinbottom, a British sailor, was walking…
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AAV8 gene therapy and dietary insults together precipitate cholestatic liver disease in a mouse model of X-linked myotubular myopathy | Science Translational Medicine
Purified diet feeding and AAV8 therapy are precipitants of cholestatic liver injury in a mouse model of X-linked myotubular myopathy.
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Grasshopper-inspired wing design improves gliding performance | Science Robotics
Aerodynamic characteristics of flying insects inspire the design of biomimetic wings with improved gliding performance.
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Chaperone-mediated autophagy supports organ regeneration and fibroblast quiescence in mouse models of fibrosis | Science Translational Medicine
LAMP2A functions as a broad-spectrum antifibrotic factor that simultaneously inhibits fibroblast activation and promotes organ regeneration.
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The codevelopment of soft robotics and assistive technology | Science Robotics
Fostering relationships between the disability and soft robotics communities will spark innovations that could benefit all.
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Baloxavir alleviates severe disease and viremia in ferrets infected with avian- or bovine-origin influenza A(H5N1) virus | Science Translational Medicine
Treating A(H5N1) influenza virus–infected ferrets with baloxavir resulted in greater survival, decreased viremia, and reduced neurotransmission.
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Neutrophil-mediated delivery of antibiotics across the tympanic membrane for otitis media treatment in a preclinical model | Science Translational Medicine
Innate neutrophils were leveraged to deliver antibiotic-containing liposomes across the intact tympanic membrane to treat acute otitis media.
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Antibody cocktails based on the occupationally acquired immunity of pediatricians neutralize and confer protection against RSV and hMPV | Science Translational Medicine
Antibody cocktails derived from pediatricians cooperatively neutralize and protect rodents against RSV and hMPV by targeting conserved epitopes.
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