- CLINICAL BRIEFINGS
A phase II trial shows that the risk of cancer…
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Facile induction of immune tolerance by an interleukin-2–TGFβ surrogate agonist
Mice
Six-to-eight-week-old female and male C57BL/6 J mice (IMSR_JAX:000664), as well as other strains, were purchased from The Jackson Laboratory. OT-II (IMSR_JAX:004194) and Thy1.1 (IMSR_JAX:000406) mice were crossed to generate OT-II Thy1.1…
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Using mosquitoes to vaccinate bats could curb the spread of deadly diseases
Fruit bats carry Nipah virus, which has infected people in India and several other countries.Credit: C. K Thanseer/DeFodi images via Getty
Mosquitoes that have been designed to carry vaccines in their saliva have been used to inoculate bats…
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Marriage of adolescent girls in Nigeria reduced by 80% by ‘big push’ intervention
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A mechanism to initiate emergency type 2 myelopoiesis
Animal studies
All animal studies were performed in accordance with UK Home Office regulations with approval by the University of Oxford Animal Welfare and Ethical Review Body (project license number 30/3359, PP2240412 and PP3246892) and the…
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A silicon chip that enables the creation of 4D cameras
Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00727-1
The development of an affordable, low-power and scalable sensor to map the position and velocity of 3D objects in a dynamically evolving scene has so far proved difficult. An…
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Immune evasive DNA donors and recombinases license kilobase-scale writing
Gaj, T., Sirk, S. J. & Barbas, C. F. Expanding the scope of site-specific recombinases for genetic and metabolic engineering. Biotechnol. Bioeng. 111, 1–15 (2014).
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Snapshots of the dynamic basis of NTSR1 G protein subtype promiscuity
Expression and purification of G protein heterotrimer
G protein heterotrimer was expressed as described14 in Tni cells (Expression Systems; isolated from Trichoplusia ni; no validation or mycoplasma testing) with viruses for Gα, Gβγ and Ric-8a…
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Optimization of an additively manufactured self-supporting lattice-filled clevis component under combined loading
Yuan, S. Fundamentals and processes of fluid pressure forming technology for complex thin-walled components. Engineering 7 (3), 358–366. https://doi.org/10.1016/j.eng.2020.08.014 (2021).
Bao,…
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‘Virtual cell’ simulates nearly every chemical reaction in the real thing
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