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  • Decoding mechanosensitive genes in cardiac fibroblasts via 3D hydrogel models of fibrosis

    Decoding mechanosensitive genes in cardiac fibroblasts via 3D hydrogel models of fibrosis

    Animal experiments

    All experimental procedures were conducted in strict accordance with the institutional guidelines provided by the Care and Use of Laboratory. The animals were supplied by the Experimental Animal Center of Xi’an Jiaotong…

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  • Pay gap between nationals and migrants mainly due to unequal access to high-paying jobs

    Pay gap between nationals and migrants mainly due to unequal access to high-paying jobs

    Pay gap between nationals and migrants mainly due to unequal access to high-paying jobs

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  • Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques

    Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques

    FP Targeting Immunogen Design and Immunization regimen

    Previous FP studies with non-glycosylated trimers around the FP have resulted in Ab responses biased towards the glycan deletions13,23. Instead, we hypothesized that a more conservative glycan…

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  • Deterministic and fractional-order modeling of measles dynamics with harmonic mean incidence rate and quarantine impact

    Deterministic and fractional-order modeling of measles dynamics with harmonic mean incidence rate and quarantine impact

    Definition

    Time fractional derive (AB) with fractional order \(\kappa\) is defined as follows42:

    $$^{AB}{_i} \wp_{b}^{i} f(t) = \frac{h(k)}{{(1 – k)}}\smallint_{i}^{b} P_{q} \frac{{ – k(b – t)^{k} }}{1 -…

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  • When will dengue strike? Outbreaks sync with heat and rain

    When will dengue strike? Outbreaks sync with heat and rain

    The Aedes mosquitos, which spread dengue, thrive in warm conditions. Credit: Soumyabrata Roy/NurPhoto via Getty

    Major dengue outbreaks in the Americas tend to occur about five months after an El Niño event — the periodic warming of the Pacific…

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  • Time’s arrow

    Time’s arrow

    Forget all the nonsense you heard about time travel. You can’t go back and kill your grandfather. The past has already happened. Everything is linked, each event underpins the next, everything is determined; you can’t do anything to break…

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  • Real-time congestion control using cascaded LSTM deep neural networks for deregulated power markets

    Real-time congestion control using cascaded LSTM deep neural networks for deregulated power markets

    IEEE 30 bus system

    The proposed method tested on the IEEE 30 Bus System consists of six generators, twenty-one loads, and forty-one branches. The incremental and decremental generator bids for CM are listed in Table A in the Online Appendix. Deep…

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  • Integration of biomimetic organoid-on-chip and 2D models advances the mechanistic Understanding of STEAP3-mediated regulation in intestinal viral infection

    Integration of biomimetic organoid-on-chip and 2D models advances the mechanistic Understanding of STEAP3-mediated regulation in intestinal viral infection

    STEAP3 deficiency impaired the antiviral effects of FAC

    STEAP3 functions as a ferrireductase, facilitating the reduction of Fe³⁺ to ferrous iron (Fe²⁺), thereby playing a pivotal role in iron homeostasis. Notably,…

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  • Autologous haematopoietic stem cell transplantation for rheumatic diseases: best practice recommendations from the EBMT Practice Harmonization and Guidelines Committee

  • Global, regional, and national burden of rheumatoid arthritis, 1990-2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021. Lancet Rheumatol. 2023: e594-e610. https://doi.org/10.1016/s2665-9913(23)00211-4.

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