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Chip-based beam…
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A large-scale coherent 4D imaging sensor
Design and fabrication
Photonic device and circuit-level simulations were performed using ANSYS Lumerical tools, whereas the integrated electronics followed a design flow using Cadence Virtuoso.
The finalized design was verified against the design…
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Computer-aided diagnosis of neonatal acute bilirubin encephalopathy with multi-modal MRI images and convolutional neural networks
Bhutani, V. K. et al. Predischarge screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. J. Pediatr. 162 (3), 477–486 (2013).
Han, J. H. & Xu, Q. Y….
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Natural maternal immunity protects neonates from Escherichia coli sepsis
Stoll, B. J. et al. Early-onset neonatal sepsis 2015 to 2017, the rise of Escherichia coli, and the need for novel prevention strategies. JAMA Pediatr. 174, e200593 (2020).
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Intestinal interoceptive dysfunction drives age-associated cognitive decline
Mice
Unless noted otherwise, young female (8 weeks old) and male (4 weeks old) C57BL/6 mice were obtained from The Jackson Laboratory and old mice (18 months old) were acquired from the National Institute on Aging. For co-housing, mice were housed…
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Facile induction of immune tolerance by an interleukin-2–TGFβ surrogate agonist
Mice
Six-to-eight-week-old female and male C57BL/6 J mice (IMSR_JAX:000664), as well as other strains, were purchased from The Jackson Laboratory. OT-II (IMSR_JAX:004194) and Thy1.1 (IMSR_JAX:000406) mice were crossed to generate OT-II Thy1.1…
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Auto-crosslinking sporesilk fibers promote endospore and Cry toxin clustering
Aronson, A. I., Beckman, W. & Dunn, P. Bacillus thuringiensis and related insect pathogens. Microbiol. Rev. 50, 1–24 (1986).
Musso, D., Ko, A. I. & Baud, D. Zika virus infection—after the…
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Ageing promotes metastasis via activation of the integrated stress response
Mice and in vivo studies
KrasLSL-G12D/+Trp53flox/flox mice (designated as KP)60 were maintained on a mixed C57BL/6-129/Sv genetic background. Lung tumours were induced in young KP (2–3 months old; referred to as KP-Young) and old KP…
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Using mosquitoes to vaccinate bats could curb the spread of deadly diseases
Fruit bats carry Nipah virus, which has infected people in India and several other countries.Credit: C. K Thanseer/DeFodi images via Getty
Mosquitoes that have been designed to carry vaccines in their saliva have been used to inoculate bats…
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Gut microbes affect cognition during ageing
Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00492-1
As mice age, changes in the microorganisms in their guts contribute to cognitive decline by altering signalling between the gut and brain.
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