Computational tools that predict which amino acid sequences are produced by cleavage enzymes can accelerate the discovery of bioactive peptides with therapeutic potential. A study recently published in Nature presents a peptide prediction…
Category: 5. Biology
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A High-Fat Diet Weakens Immunity in a Mouse Model
Obesity rates have been steadily rising around the world for many years. Obesity has been linked to a variety of health problems including metabolic disorders such as type 2 diabetes and cardiovascular…
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Chinese Blackbirds Are Mimicking Electric Moped Alarms
Chinese Blackbirds can mimic electric moped alarms, though their imitations are simplified. A new study shows this mimicry is more common than expected and may involve copying both the source and other birds, prompting further research into urban…
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New light-driven process could accelerate the discovery of new drugs
Researchers at Indiana University and Wuhan University in China have unveiled a groundbreaking chemical process that could streamline the development of pharmaceutical compounds, chemical building blocks that influence how drugs…
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Asgard archaea provide clues to the origin of complex life forms
Ten years ago, nobody knew that Asgard archaea even existed. In 2015, however, researchers examining deep-sea sediments discovered gene fragments that indicated a new and previously undiscovered form of microbes.
With computer…
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Bacteria use dormant phages to create immunity against viral invaders
Like people, bacteria get invaded by viruses. In bacteria, the viral invaders are called bacteriophages, derived from the Greek word for bacteria-eaters, or in shortened form, “phages.” Scientists have sought to learn how the…
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Advanced imaging technique reveals how nuclear pores regulate molecular movement
Just as cities must carefully manage the flow of cars in and out of downtown, cells regulate the movement of molecules into and out of the nucleus. This microscopic metropolis relies on an intricate gateway – facilitated by nuclear…
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NAT10-mediated N4-acetylcytidine modification in KLF9 mRNA promotes adipogenesis
Specimen collected
Human tissues were collected from different patients (n = 4) who suffered from abdomen trauma. The remaining tissues of SATs, VATs, liver, spleen and small intestine were obtained through surgery. The SATs and VATs were…
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Uncovering the viral aetiology of undiagnosed acute febrile illness in Uganda using metagenomic sequencing
Patient demographics
Within the AFI cohort of 1281 patients, the median age was 18 years (IQR 7–30 years). 717 participants (56%) were female and 564 (44%) male. 382 (30%) patients were recruited from central Uganda (Wakiso), 450 (35%) from…
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Current use of donor lymphocyte infusions after allogenic stem cell transplantation in Europe: a survey on behalf of the cellular therapy and immunobiology working party of the EBMT
Horowitz MM, Gale RP, Sondel PM, Goldman JM, Kersey J, Kolb HJ, et al. Graft-versus-leukemia reactions after bone marrow transplantation. Blood. 1990;75:555–62.
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