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Category: 5. Biology
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Reply to: About proteins of a siphophage tail tip complex reverting to their pre-ejection fold after DNA ejection
replying to C. A. Arnaud et al. Nature Communications https://doi.org/10.1038/s41467-025-57874-8 (2025)
In a recent Matters Arising, Arnaud et al. critically reviewed our recent work on the structure…
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Dynamic synthesis and transport of phenazine-1-carboxylic acid to boost extracellular electron transfer rate
Construction and optimization of the PCA biosynthesis pathway in S. oneidensis
Using S. oneidensis MR-1, we found that the addition of PCA at ~80 µM resulted in the highest power generation, which was significantly…
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Inhibiting hedgehog signal by a patched-1 antibody
The Hedgehog (HH) signaling pathway is crucial for the developmental patterning of animal embryogenesis and the regeneration of adult tissues1. The aberrant activation of HH signaling has been linked…
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Kinetically activating nanovaccine mimicking multidimensional immunomodulation of natural infection for broad protection against heterologous viruses in animal models
Materials and reagents
Alhydrogel adjuvant 2% (alum, cat. no. vac-alu-50) and Adju-Phos adjuvant (AdjuPhos, cat. no. vac-phos-250) were purchased from InvivoGen (San Diego, CA, USA). Ovalbumin from chicken egg white (OVA, cat. no. A5503) and…
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A Csde1-Strap complex regulates plasma cell differentiation by coupling mRNA translation and decay
Identification of differentiation stage-specific RBPomes via mRNA-interactome capture
We performed mRNA interactome capture (RIC) to identify RBPs expressed at different stages of plasma cell differentiation in an in vitro culture system mimicking…
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Enzymatic cleavage of model lignin dimers depends on pH, enzyme, and bond type
Enzyme activity screening
pH is hypothesized to be one of the most important conditions for enzymatic depolymerization of lignin polymers. pH influences the degree of polymerization versus depolymerization by LMEs24and developing LMEs that…
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Ghost Frog Found: Scientists Stumble Upon Species Missing Since 1902
The elusive frog Alsodes vittatus has been found after 130 years, emphasizing gaps in knowledge and conservation needs in South American amphibians. A team of researchers has rediscovered a frog species that had not been seen in over 130 years….
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Biologists discover ancient neurohormone that controls appetite
A team of biologists at Queen Mary University of London has discovered that a neurohormone controlling appetite in humans has an ancient evolutionary origin, dating back over half a billion years. The findings, published in Proceedings of the…
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