Category: 5. Biology

Continue Reading

  • Microbial degradation of flubendiamide in different types of soils at tropical region using lactic acid bacteria formulation

    Microbial degradation of flubendiamide in different types of soils at tropical region using lactic acid bacteria formulation

    Chemicals and reagents

    The analytical standards of flubendiamide (98% purity) and desido flubendiamide (99.8% purity) were purchased from Sigma-Aldrich. HPLC-grade acetonitrile (CH3CN), anhydrous magnesium sulfate (MgSO4), and analytical-grade of…

    Continue Reading

  • EPS8L2 drives colorectal cancer cell proliferation and migration via YBX1-dependent activation of G3BP2 transcription

    EPS8L2 drives colorectal cancer cell proliferation and migration via YBX1-dependent activation of G3BP2 transcription

    DEGs, GO, and KEGG analysis

    Two GEO datasets (GSE75970 and GSE103512) were downloaded from the Gene Expression Omnibus (GEO: https://www.ncbi.nlm.nih.gov/geo). The TCGA+GTEx dataset was obtained from the TCGA and GTEx databases. DEGs analysis was…

    Continue Reading

  • Association of HLA-DRA expression with prognosis and tumor microenvironment in clear cell renal cell carcinoma

    Association of HLA-DRA expression with prognosis and tumor microenvironment in clear cell renal cell carcinoma

  • Siegel, R. L., Miller, K. D. & Jemal, A. Cancer statistics, 2020. CA Cancer J. Clin. 70(1), 7–30 (2020).

    PubMed 

    Google Scholar 

  • Nabi, S., Kessler, E. R., Bernard, B., Flaig, T. W. & Lam, E. T. Renal…

  • Continue Reading

  • Evaluating the prognostic value of microbial communities in predicting recurrence of laryngeal carcinoma: a multicenter case-control study

    Evaluating the prognostic value of microbial communities in predicting recurrence of laryngeal carcinoma: a multicenter case-control study

    Recurrent LSCC characteristics and microbial community composition

    We characterized the microbial communities of formalin-fixed paraffin-embedded (FFPE) tissue samples from 123 patients with LSCC in the LSCC cohort. Overall, a total of 180 LSCC…

    Continue Reading

  • Improving early detection of Alzheimer’s disease through MRI slice selection and deep learning techniques

    Improving early detection of Alzheimer’s disease through MRI slice selection and deep learning techniques

    In this study, images including axial brain slices and T1-weighted structural MRI data were used to diagnose Alzheimer’s disease. EfficientNetB2, InceptionV3, Regnetx006 and the proposed new models were employed on 224 × 224 rescaled MRI…

    Continue Reading

  • Generalized linear modeling of flow cytometry data to analyze immune responses in tuberculosis vaccine research

    Generalized linear modeling of flow cytometry data to analyze immune responses in tuberculosis vaccine research

  • Geneva: World Health Organization. Global Tuberculosis Report 2023. (ed World Health Organization). https://iris.who.int/ (World Health Organization, 2023).

  • Choi, Y. H. et al. Safety and immunogenicity of the ID93 + GLA-SE tuberculosis vaccine in…

  • Continue Reading

  • F-actin disassembly by the oxidoreductase MICAL1 promotes mechano-dependent VWF-GPIbα interaction in platelets

    F-actin disassembly by the oxidoreductase MICAL1 promotes mechano-dependent VWF-GPIbα interaction in platelets

    A list of reagents and antibodies can be found in Supplementary Data 1.

    Animals

    This project was approved by the local ethical committee CEEA26 and the French government under the number APAFIS#25086-2020032312267714. Mical1fl/fl mice were kindly…

    Continue Reading

  • Computational machine learning estimation of digitoxin solubility in supercritical solvent at different temperatures utilizing ensemble methods

    Computational machine learning estimation of digitoxin solubility in supercritical solvent at different temperatures utilizing ensemble methods

  • Csicsák, D. et al. The effect of the particle size reduction on the biorelevant solubility and dissolution of poorly soluble drugs with different acid-base character. Pharmaceutics 15(1), 278 (2023).

    PubMed 
    PubMed Central 

  • Continue Reading

  • Afatinib amplifies cAMP-induced fluid secretion in a mouse mini-gut model via TMEM16A-mediated fluid secretion and secretory cell differentiation

    Afatinib amplifies cAMP-induced fluid secretion in a mouse mini-gut model via TMEM16A-mediated fluid secretion and secretory cell differentiation

    Ethics statements

    This study has been approved by the Faculty of Science, Mahidol University Animal Care and Use Committee SCMU-ACUC Review (Protocol number: MUSC67-006-711), and all experiments were conducted in accordance with relevant…

    Continue Reading