Scientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between bipolar disorder and rare loss-of-function variants in two genes.
Bipolar disorder is characterized by extreme mood swings,…
Category: 5. Biology
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How Fast Is Your Immune System Aging? Scientists Just Built a Clock To Find Out
The HZI team has developed an AI-powered computer model that, for the first time, reveals the aging process at the cellular level. As we age, our immune system ages as well. We become more susceptible to infections, vaccinations become less…
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Research identifies pressure-sensing protein behind gut motility
After every meal, the intestines perform an action called peristalsis – moving food through their hollow interiors with coordinated contractions and relaxations of the smooth muscle.
For more than a century, scientists have known…
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ELRIG announces Prof Rory Johnson and Dr Shalini Andersson as keynote speakers at Therapeutic Oligonucleotides 2025
ELRIG, a not-for-profit, volunteer-led organization for the drug discovery community, today announced the keynote speakers for Therapeutic Oligonucleotides 2025 taking place at the AstraZeneca R&D site in Gothenburg, Sweden from…
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The Tentacled Microbes That Might Have Sparked Complex Life
New research sheds light on one of the biggest questions in biology: where did complex life come from? The answer may lie with Asgard archaea, a group of ancient single-celled microbes that share surprising similarities with more complex…
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Ancient appetite-control molecule found in starfish and humans
A team of biologists at Queen Mary University of London has discovered that a neurohormone controlling appetite in humans has an ancient evolutionary origin, dating back over half a billion years. The findings, published in…
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New chromatin tracing method unlocks DNA looping process in high resolution
Among the many marvels of life is the cell’s ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA – its genome – and segregate it equally into two new daughter…
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Computational drug design for neurosyphilis disease by targeting Phosphoglycerate Kinase in Treponema pallidum with enhanced binding affinity and reduced toxicity
Structure retrieval of the target protein
The 3D structures were retrieved from three tools: I-TASSER, Robetta, and AlphaFold. Among these, the AlphaFold structure was selected ID (B2S3D0). The alignment graph from Alphafold represents the…
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Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors
Next-day reporting of molecular diagnostic results
After a proof-of-concept preliminary version19, Rapid-CNS2 was run independently at two centers on fresh or cryopreserved tumor tissue (University Hospital Heidelberg, Germany and University of…
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