Table 1 presents a summary of the acceptable storage times according to the main text of the CLSI H21-ED6 guideline and our findings. First, we focused on room-temperature and refrigerated storage. As shown in Table 1, the acceptable storage…
Category: 5. Biology
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PD-L1+ plasma cells suppress T lymphocyte responses in patients with sepsis and mouse sepsis models
Experimental design: mice cohorts
Male C57BL/6 J mice (strain code = #632, IMSR_JAX #000664, Charles River, L’Arbresle, France) and VertX mice containing Il10-eGFP-reporter (IMSR_JAX #014530, The Jackson Laboratory, ME, USA), aged between…
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Author Correction: Global warming risks dehydrating and inflaming human airways
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or…
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Tutorial: guidelines for quality filtering of whole-exome and whole-genome sequencing data for population-scale association analyses
Karczewski, K. J. et al. The mutational constraint spectrum quantified from variation in 141,456 humans. Nature 581, 434–443 (2020).
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Taliun, D. et…
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Atomic context-conditioned protein sequence design using LigandMPNN
Methods for training LigandMPNN for sequence design
Training data
LigandMPNN was trained on a dataset similar to ProteinMPNN28. We used protein assemblies in the PDB (as of 16 December 2022) determined by X-ray crystallography or cryo-electron…
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A vision attention driven Language framework for medical report generation
The present work describes the development of a framework for generating text from images, which is based on the utilisation of tags from medical reports. The general framework of the study is shown in Fig. 1. The framework consists of two…
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Understanding the machinery that reads the genome
Understanding the machinery that reads the genome
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Transcriptomics in the era of long-read sequencing
Conesa, A. et al. A survey of best practices for RNA-seq data analysis. Genome Biol. 17, 13 (2016). This review provides an overview of short-reads transcriptomics experimental design and bioinformatic analysis.
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Resident tissue macrophages maintain intraocular pressure by regulating extracellular matrix homeostasis
Glaucoma is a neurodegenerative disease characterized by increased intraocular pressure (IOP), ultimately leading to optic nerve damage and irreversible vision loss. IOP is primarily regulated by the conventional outflow tract — consisting of…
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In vitro and in silico pharmacological effects of Rosmarinus officinalis leaf methanolic extracts and essential oils
Akacha, B. B. et al. Recent advances in phytochemistry, pharmaceutical, biomedical, phytoremediation, and bio-preservative applications of Lobularia maritima. S. Afr. J. Bot. 165, 202–216 (2024).
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