Category: 5. Biology

AI systems already work their magic in many areas of biomedical science, helping to solve protein structure, discover hidden patterns in the genome and process massive amounts of biological data. Now, an AI-assisted technology developed at the…

A new study found that patients with long COVID often feel they have to prove their illness is physical to be taken seriously. This can lead them to reject psychological support for fear that it implies…

Ethics

The study adhered to all applicable regulations governing the use of human participants and was conducted in accordance with the principles of the Declaration of Helsinki. Participants in the FinnGen study provided informed consent for…

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This is a summary of: Heo, D. et al. Transcriptional profiles of mouse oligodendrocyte precursor cells across…

Mitochondrial DNA (mtDNA) disorders are usually heteroplasmic, with cells harboring both wild-type and mutated mtDNA. They may become apparent once the number of affected mitochondria reaches a certain level. The threshold varies from tissue to…

Identification and correlation analysis of key genes in HF

This study searched for gene expression profile datasets related to HF in the GEO database using the keyword ‘heart failure’. Several HF datasets, including GSE76701, GSE57338,…

MMT involved in LPS-induced pulmonary fibrosis

SAPF mouse models were established as shown in Supplementary Fig. 1a. Pulmonary injury and collagen deposition were assessed using H&E and Masson staining, showing significant interstitial leukocyte…

Synthesis of DMGV standards

Generally, the chemical synthesis of ADMA went through a six-step reaction, starting from Boc-Orn(Z)-OH (Suppl. Fig. S1A). During this process, silica gel-based purification was required after each reaction step of…

Isolation and characterization of antibodies targeting MPXV M1R and B6R

In this study, we employed phage surface display technology to identify a diverse and extensive array of antibodies targeting M1R and B6R proteins on the surface of MPXV…