For patients with polycystic kidney disease (PKD), a common genetic disorder that ravages the waste-removing organ with cysts, dialysis and transplantation are among the only treatments.
More than 12.4 million people worldwide…
Category: 5. Biology
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How to talk for a very, very long time
Most of us will never have to speak in public for 25 hours and 5 minutes straight the way that Sen. Cory Booker (D-New Jersey) did from March 31 into April 1. During his recording-breaking speech, the Garden State’s senior senator was…
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120 Years of Conservation Efforts Pay Off: Yellowstone Bison Are Now a Single Super Herd
Originally made up of two distinct herds, researchers now believe the Yellowstone bison should be managed as a single, interbreeding population. Researchers from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) have…
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NUZ-001 shows positive results in human 3D brain model
Neurizon Therapeutics Limited (“Neurizon”), a clinical-stage biotech company dedicated to advancing treatments for neurodegenerative diseases, is pleased to advise that results from an independent study undertaken in…
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4basebio receives MHRA GMP licence for manufacture and supply of synthetic DNA
4basebio PLC (AIM: 4BB) (“4basebio”), a company which develops and commercializes the large-scale manufacture of synthetic DNA as well as nanoparticle delivery solutions, today announced that it has received Good Manufacturing…
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Genetic research offers hope for children with rare intestinal disorders
At only two days old, Sophie was losing too much weight, and too quicky.
Further genetic testing would show that Sophie has one of a group of rare conditions called CODE (congenital diarrhea and enteropathies) that disrupts the…
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It Looks Like Nothing Else: Meet the Bizarre Frog That Shouldn’t Exist
The Leyte Chorus Frog is a rare, non-reproducing hybrid caused by deforestation-driven overlap between two frog species, finally identified using modern genomics and decades-old museum specimens. Evolutionary biologists working in the Philippines…
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EchoBack CAR T-cells could be a game changer in cancer immunotherapy
Imagine a super-charged immune cell that can launch a focused attack on stubborn solid tumors – a smart fighter that destroys cancer cells for days without tiring. USC biomedical engineers have made this concept a reality, crafting…
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Monkeys are world’s best yodellers — new research
A new study has found that the world’s finest yodellers aren’t from Austria or Switzerland, but the rainforests of Latin America.
Published in the journal Philosophical Transactions of the Royal Society B and led by experts from Anglia Ruskin…
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Jorunnamycin A induces apoptosis in pancreatic ductal adenocarcinoma cells, spheroids, and patient-derived organoids by modulating KRAS-mediated survival pathways
High binding affinity between JA and KRAS G12D
In silico molecular docking analysis was conducted to predict the interactions between JA and wild-type (WT) KRAS, as well as its mutant variants (G12D, G12V, and G12C) (Fig. 2). The docking…
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