Category: 5. Biology

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  • Multi-proton dynamics near membrane-water interface

    Multi-proton dynamics near membrane-water interface

    Initial conditions

    In the final DFTB3 equilibrated geometry for a hydrated POPC membrane (see Methods), we replaced one, two, or three water molecules with hydronium ions (H3O+) at different positions. Then we performed DFTB3 production runs at…

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  • Development and validation of interpretable machine learning models to predict distant metastasis and prognosis of muscle-invasive bladder cancer patients

    Development and validation of interpretable machine learning models to predict distant metastasis and prognosis of muscle-invasive bladder cancer patients

    Demographic and clinical baseline characteristics

    To develop a predictive model for distant metastasis, data from 43,951 MIBC patients in the SEER database and 125 MIBC patients from The First Affiliated Hospital of Henan University of Science and…

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  • Application of new biologic disease criteria for synucleinopathies to the systemic synuclein sampling study cohort

  • Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA

    L. M. Chahine & S. Mosovsky

  • Department of Biostatistics, University of Iowa College of Public Health, Iowa City, IA, USA

    M. C. Brumm, A. R. Nair, Michael C. Brumm, Chelsea…

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  • Life on the dry side: a roadmap to understanding desiccation tolerance and accelerating translational applications

    Life on the dry side: a roadmap to understanding desiccation tolerance and accelerating translational applications

  • Walters, C., Hill, L. M. & Wheeler, L. J. Dying while dry: kinetics and mechanisms of deterioration in desiccated Organisms1. Integr. Comp. Biol. 45, 751–758 (2005).

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  • ROBO1 enhanced esophageal carcinoma cell radioresistance through accelerating G3BP2-mediated eIF3A degradation

    ROBO1 enhanced esophageal carcinoma cell radioresistance through accelerating G3BP2-mediated eIF3A degradation

    Cell culture

    Human esophageal carcinoma cell lines KYSE450 and TE1 (HyCyte, Suzhou, China) were incubated in RPMI Medium 1640 basic (Gibco, USA) containing 10% fetal bovine serum (OriCell, China) and 1% Penicillin-Streptomycin Solution (Biosharp,…

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  • Striatal dopamine tone is positively associated with adiposity in humans as determined by PET using dual dopamine type-2 receptor antagonist tracers

    Striatal dopamine tone is positively associated with adiposity in humans as determined by PET using dual dopamine type-2 receptor antagonist tracers

    Sixty-one adults provided informed consent to participate in a dual PET radiotracer study investigating the relationship between D2R availability and BMI under controlled dietary conditions (ClinicalTrials.gov NCT03648892). Participants were…

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  • Effects of anthropogenic noise on marine mammal abundances informed by mixed methods

    Effects of anthropogenic noise on marine mammal abundances informed by mixed methods

    Study Location

    The Harbor Seal colony studied is located on the Hopkins Marine Station (HMS) of Stanford University within the Monterey Bay National Marine Sanctuary (MBNMS) and the Lover’s Point-Julia Platt State Marine Reserve (LPJPSMR) in…

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  • GRASPs link Reelin to the Golgi during neocortical development to control neuronal migration and dendritogenesis

    GRASPs link Reelin to the Golgi during neocortical development to control neuronal migration and dendritogenesis

  • Jossin, Y. Molecular mechanisms of cell polarity in a range of model systems and in migrating neurons. Mol. Cell Neurosci. 106, 103503 (2020).

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  • Nadarajah, B., Brunstrom, J. E.,…

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  • VGG-MFO-orange for sweetness prediction of Linhai mandarin oranges

    VGG-MFO-orange for sweetness prediction of Linhai mandarin oranges

    Experimental configurations

    The model described in this paper was trained and validated in the environment shown in Table 4, and the experimental parameters of the network model were set as shown in Table 5.

    Table 4 The experimental environment…

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